Twenty years ago, the discovery of peptides able to cross cellular membranes launched a
novel field in molecular delivery based on these non-invasive vectors, most commonly …

The ability of cell-penetrating peptides (CPPs) to cross cell membranes has found numerous
applications in the delivery of bioactive compounds to the cytosol of living cells. Their …

Recent molecular-dynamics simulations have suggested that the arginine-rich HIV Tat
peptides translocate by destabilizing and inducing transient pores in phospholipid bilayers …

Cell-penetrating peptides (CPPs) traverse the membrane of biological cells at low
micromolar concentrations and are able to take various cargo molecules along with. Despite …

Cell-penetrating peptides (CPPs) have recently gained considerable interest due to their
ability to cross cellular membranes and deliver macromolecular cargo. It is of great …

Delivery of macromolecules into living cells by arginine-rich cell penetrating peptides (AR-
CPPs) is an important new avenue for the development of novel therapeutic strategies …

Despite continuing advances in the development of macromolecules, including peptides,
proteins, and oligonucleotides, for therapeutic purposes, the successful application of these …

A large number of surfactants (surface active molecules) are chemically simple compounds
that can be obtained by simple chemical reactions, in some cases even under presumably …

Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of
new information on the use of these peptides as transport systems has in fact served to …

Independently from the cell penetrating peptide uptake mechanism (endocytic or not), the
interaction of the peptide with the lipid bilayer remains a common issue that needs further …