The life and times of a tRNA
EM Phizicky, AK Hopper - RNA, 2023 - rnajournal.cshlp.org
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
Editing and methylation at a single site by functionally interdependent activities
MAT Rubio, KW Gaston, KM McKenney, IMC Fleming… - Nature, 2017 - nature.com
Nucleic acids undergo naturally occurring chemical modifications. Over 100 different
modifications have been described and every position in the purine and pyrimidine bases …
modifications have been described and every position in the purine and pyrimidine bases …
S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates
L Han, E Marcus, S D'Silva, EM Phizicky - Rna, 2017 - rnajournal.cshlp.org
The 3-methylcytidine (m3C) modification is ubiquitous in eukaryotic tRNA, widely found at
C32 in the anticodon loop of tRNAThr, tRNASer, and some tRNAArg species, as well as in …
C32 in the anticodon loop of tRNAThr, tRNASer, and some tRNAArg species, as well as in …
Multi-substrate specificity and the evolutionary basis for interdependence in tRNA editing and methylation enzymes
S Dixit, JC Henderson, JD Alfonzo - Frontiers in genetics, 2019 - frontiersin.org
Among tRNA modification enzymes there is a correlation between specificity for multiple
tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved …
tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved …
Dissecting Trypanosoma brucei RRP44 function in the maturation of segmented ribosomal RNA using a regulated genetic complementation system
EP Guerra-Slompo, G Cesaro… - Nucleic Acids …, 2023 - academic.oup.com
Trypanosoma brucei belongs to a group of protozoans presenting fragmented large subunit
rRNA. Its LSU rRNA equivalent to the 25S/28S rRNA of other eukaryotes is split into six …
rRNA. Its LSU rRNA equivalent to the 25S/28S rRNA of other eukaryotes is split into six …
Trypanosoma brucei RRP44 is involved in an early stage of large ribosomal subunit RNA maturation
Ribosomal RNA precursors undergo a series of structural and chemical modifications to
generate matured RNA molecules that will comprise ribosomes. This maturation process …
generate matured RNA molecules that will comprise ribosomes. This maturation process …
Binding synergy as an essential step for tRNA editing and modification enzyme codependence in Trypanosoma brucei
KM McKenney, MAT Rubio, JD Alfonzo - RNA, 2018 - rnajournal.cshlp.org
Transfer RNAs acquire a variety of naturally occurring chemical modifications during their
maturation; these fine-tune their structure and decoding properties in a manner critical for …
maturation; these fine-tune their structure and decoding properties in a manner critical for …
TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei
D Faktorová, A Bär, H Hashimi, K McKenney… - Molecular and …, 2018 - Elsevier
Ribosome biosynthesis, best studied in opisthokonts, is a highly complex process involving
numerous protein and RNA factors. Yet, very little is known about the early stages of pre-18S …
numerous protein and RNA factors. Yet, very little is known about the early stages of pre-18S …
Earth's seven sisters
IAG Snellen - Nature, 2017 - nature.com
Earth's seven sisters | Nature Skip to main content Thank you for visiting nature.com. You are
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RNA editing packs a one-two punch
WT Yewdell, J Chaudhuri - Nature, 2017 - nature.com
RNA editing packs a one-two punch | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …
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