The process of transcription termination is essential to proper expression of bacterial genes
and, in many cases, to the regulation of bacterial gene expression. Two types of bacterial …

Bifidobacterium is a non-spore-forming, Gram-positive, anaerobic probiotic actinobacterium
and commonly found in the gut of infants and the uterine region of pregnant mothers. Like all …

Large genetic engineering projects require more cistrons and consequently more strong and
reliable transcriptional terminators. We have measured the strengths of a library of …

Escherichia coli is a widely used host organism for recombinant technology and the
bacterial incorporation of non-natural amino acids promises the efficient synthesis of …

Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections
with symptoms ranging from mild diarrhea to fulminant colitis. Cyclic diguanosine …

Rickettsia species of the spotted fever group are arthropod-borne obligate intracellular
bacteria that can cause mild to severe human disease. These bacteria invade host cells …

Soil-dwelling microbes solubilize mineral phosphates by secreting gluconic acid, which is
produced from glucose by a periplasmic glucose dehydrogenase (GDH) that requires …

Spotted fever group (SFG) rickettsiae are human pathogens that infect cells in the
vasculature. They disseminate through host tissues by a process of cell-to-cell spread that …

Natural products (NPs), also known as secondary metabolites, are produced in bacteria,
fungi, and plants. NPs represent a rich source of antibacterial, antifungal, and anticancer …

A fixed gene copy number is important for the in silico construction of engineered synthetic
networks. However, the copy number of integrated genes depends on their genomic …