Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

RJ Obaid, N Naeem, EU Mughal, MM Al-Rooqi… - RSC …, 2022 - pubs.rsc.org
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

[HTML][HTML] Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects

H Khan, S Amin, MA Kamal, S Patel - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Abstract Background Acetylcholinesterase (AChE), a serine hydrolase, is primarily
responsible for the termination of signal transmission in the cholinergic system, owing to its …

The cellular and molecular processes associated with scopolamine-induced memory deficit: A model of Alzheimer's biomarkers

K San Tang - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) is neurodegenerative disorder that is associated with memory and
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …

Dietary polyphenols: A multifactorial strategy to target Alzheimer's disease

S Dhakal, N Kushairi, CW Phan, B Adhikari… - International journal of …, 2019 - mdpi.com
Ageing is an inevitable fundamental process for people and is their greatest risk factor for
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …

Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases

M Zhang, L Xu, H Yang - International Journal of Molecular Sciences, 2018 - mdpi.com
Neurological diseases (NDs) are a leading cause of death worldwide and tend to mainly
affect people under the age of 50. High rates of premature death and disability caused by …

[HTML][HTML] Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional …

GY Choi, IS Lee, E Moon, H Choi, AR Je… - Biomedicine & …, 2024 - Elsevier
Alzheimer's disease (AD) is characterized by cognitive impairment, loss of learning and
memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of …

Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress

I Brinza, MAE Raey, W El-Kashak, OA Eldahshan… - Molecules, 2022 - mdpi.com
Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring
monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote …

Neuroprotective effects of soy isoflavones on scopolamine-induced amnesia in mice

C Lu, Y Wang, D Wang, L Zhang, J Lv, N Jiang, B Fan… - Nutrients, 2018 - mdpi.com
In the recent years, interest in soybean as a neuroprotective nutrient in the management of
Alzheimer's disease (AD) has increased and soy isoflavones (SI), as kinds of soybean …

“Medicine food homology” plants promote periodontal health: antimicrobial, anti-inflammatory, and inhibition of bone resorption

S Qu, S Yu, X Ma, R Wang - Frontiers in Nutrition, 2023 - frontiersin.org
“Medicine food homology”(MFH) is a term with a lengthy history. It refers to the fact that a lot
of traditional natural products have both culinary and therapeutic benefits. The antibacterial …

Memory Recovery Effect of a New Bioactive Innovative Combination in Rats with Experimental Dementia

L Tancheva, R Kalfin, B Minchev, D Uzunova… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease manifests as a complex pathological condition, with neuroinflammation,
oxidative stress and cholinergic dysfunction being a few of the many pathological changes …