Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
[HTML][HTML] Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects
Abstract Background Acetylcholinesterase (AChE), a serine hydrolase, is primarily
responsible for the termination of signal transmission in the cholinergic system, owing to its …
responsible for the termination of signal transmission in the cholinergic system, owing to its …
The cellular and molecular processes associated with scopolamine-induced memory deficit: A model of Alzheimer's biomarkers
K San Tang - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) is neurodegenerative disorder that is associated with memory and
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …
Dietary polyphenols: A multifactorial strategy to target Alzheimer's disease
Ageing is an inevitable fundamental process for people and is their greatest risk factor for
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …
Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases
M Zhang, L Xu, H Yang - International Journal of Molecular Sciences, 2018 - mdpi.com
Neurological diseases (NDs) are a leading cause of death worldwide and tend to mainly
affect people under the age of 50. High rates of premature death and disability caused by …
affect people under the age of 50. High rates of premature death and disability caused by …
[HTML][HTML] Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional …
GY Choi, IS Lee, E Moon, H Choi, AR Je… - Biomedicine & …, 2024 - Elsevier
Alzheimer's disease (AD) is characterized by cognitive impairment, loss of learning and
memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of …
memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of …
Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress
Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring
monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote …
monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote …
Neuroprotective effects of soy isoflavones on scopolamine-induced amnesia in mice
In the recent years, interest in soybean as a neuroprotective nutrient in the management of
Alzheimer's disease (AD) has increased and soy isoflavones (SI), as kinds of soybean …
Alzheimer's disease (AD) has increased and soy isoflavones (SI), as kinds of soybean …
“Medicine food homology” plants promote periodontal health: antimicrobial, anti-inflammatory, and inhibition of bone resorption
S Qu, S Yu, X Ma, R Wang - Frontiers in Nutrition, 2023 - frontiersin.org
“Medicine food homology”(MFH) is a term with a lengthy history. It refers to the fact that a lot
of traditional natural products have both culinary and therapeutic benefits. The antibacterial …
of traditional natural products have both culinary and therapeutic benefits. The antibacterial …
Memory Recovery Effect of a New Bioactive Innovative Combination in Rats with Experimental Dementia
L Tancheva, R Kalfin, B Minchev, D Uzunova… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease manifests as a complex pathological condition, with neuroinflammation,
oxidative stress and cholinergic dysfunction being a few of the many pathological changes …
oxidative stress and cholinergic dysfunction being a few of the many pathological changes …