The fact that transposable elements (TEs) can influence host gene expression was first
recognized more than 50 years ago. However, since that time, TEs have been widely …

Cellular commitment to a specific lineage is controlled by differential silencing of genes,
which in turn depends on epigenetic processes such as DNA methylation and histone …

Biology presents many wonders, but one of the most remarkable is how a complex
multicellular organism grows from a single cell. Until recently, the processes involved …

DNA methyltransferases catalyze the transfer of a methyl group from S‐adenosyl‐l‐
methionine to cytosine or adenine bases in DNA. These enzymes challenge the …

Double-stranded RNA induces a post-transcriptional gene silencing process, termed RNAi,
in diverse organisms. It is shown here that transcriptional gene silencing accompanied by de …

RNA interference (RNAi) is an evolutionarily conserved mechanism that uses short
antisense RNAs that are generated by'dicing'dsRNA precursors to target corresponding …

In the universe of science, two worlds have recently collided—those of RNA and chromatin.
The intersection of these two fields has been impending, but evidence for such a meaningful …

Plants and filamentous fungi share with mammals enzymes responsible for DNA
methylation. In these organisms, DNA methylation is associated with gene silencing and …

Eukaryotes contain a diversified set of small RNA-guided pathways that control genes,
repeated sequences, and viruses at the transcriptional and posttranscriptional levels …

Epigenetic silencing is a natural phenomenon in which the expression of genes is regulated
through modifications of DNA, RNA, or histone proteins. It is a mechanism for defending host …