Analysis of anticancer drugs: a review

S Nussbaumer, P Bonnabry, JL Veuthey… - Talanta, 2011 - Elsevier
In the last decades, the number of patients receiving chemotherapy has considerably
increased. Given the toxicity of cytotoxic agents to humans (not only for patients but also for …

Nanomaterial-based electrochemical sensors for detection of glucose and insulin

J Hovancová, I Šišoláková, R Oriňaková… - Journal of Solid State …, 2017 - Springer
Electrochemical sensors for the detection of specific biomolecules have attracted a lot of
interest over the recent years due to their high sensitivity, selectivity, simple preparation and …

Antineoplastic drugs and their analysis: a state of the art review

N Guichard, D Guillarme, P Bonnabry… - Analyst, 2017 - pubs.rsc.org
The number of patients suffering from cancer is constantly increasing and, consequently, the
number of different chemotherapy treatments administered is increasing. Given the high …

High-performance liquid chromatographic method for the determination of gemcitabine and 2′, 2′-difluorodeoxyuridine in plasma and tissue culture media

MN Kirstein, I Hassan, DE Guire, DR Weller… - … of chromatography B, 2006 - Elsevier
Gemcitabine, a pyrimidine antimetabolite undergoes metabolism by plasma and liver
cytidine deaminase to form the inactive compound, 2′, 2′-difluorodeoxyuridine (dFdU) …

Stability‐indicating HPLC determination of gemcitabine in pharmaceutical formulations

R Singh, AK Shakya, R Naik… - International Journal of …, 2015 - Wiley Online Library
A simple, sensitive, inexpensive, and rapid stability indicating high performance liquid
chromatographic method has been developed for determination of gemcitabine in injectable …

Rapid determination of gemcitabine in plasma and serum using reversed‐phase HPLC

C Lanz, M Früh, W Thormann, T Cerny… - Journal of separation …, 2007 - Wiley Online Library
Abstract Gemcitabine (2′ 2′‐difluorodeoxycytidine) is a pyrimidine analog used in the
treatment of a variety of solid tumors. After intravenous (iv) administration, it is rapidly …

FDA-validated ecofriendly chromatographic methods for simultaneous determination of gemcitabine and sorafenib: applications to pharmacokinetics

MMZ Sharkawi, NR Mohamed, MT El-Saadi, NH Amin - Chromatographia, 2023 - Springer
Combination therapy of gemcitabine and sorafenib is synergistically effective and well
tolerated in patients with non-small cell lung cancer (NSCLC). In this study, the …

The determination of gemcitabine and 2′-deoxycytidine in human plasma and tissue by APCI tandem mass spectrometry

R Honeywell, AC Laan, CJ Van Groeningen… - … of Chromatography B, 2007 - Elsevier
A fast, sensitive and accurate method for the determination of gemcitabine
(difluorodeoxycytidine; dFdC) and deoxycytidine (CdR) in human plasma/tissue was …

[HTML][HTML] Vitamin D fortification of selected edible insect species through UVB-treatment

N Nölle, A Hörnstein, C Lambert - Food Chemistry, 2024 - Elsevier
Edible insects are attracting increased interest worldwide, because they are arguably more
sustainable than more established animal foods. Apart from being rich in protein and …

Validated assay for the simultaneous determination of the anti‐cancer agent gemcitabine and its metabolite 2′, 2′‐difluorodeoxyuridine in human plasma by high …

LD Vainchtein, H Rosing, B Thijssen… - … Journal Devoted to …, 2007 - Wiley Online Library
A sensitive and specific high‐performance liquid chromatography/tandem mass
spectrometry (HPLC/MS/MS) assay for the quantitative determination of gemcitabine (dFdC) …