Wearable Label‐Free Optical Biodetectors: Progress and Perspectives

SS Dhanabalan, S Sriram, S Walia… - Advanced Photonics …, 2021 - Wiley Online Library
Biomarkers are the primary indicators of human health. Measurements traditionally rely on
targeted binding and assays, which, in turn, rely on specific “labels” that define the …

Broadband time domain diffuse optical reflectance spectroscopy: a review of systems, methods, and applications

S Konugolu Venkata Sekar, P Lanka, A Farina… - Applied Sciences, 2019 - mdpi.com
This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

Optical characterization of porcine tissues from various organs in the 650–1100 nm range using time-domain diffuse spectroscopy

S Mosca, P Lanka, N Stone… - Biomedical optics …, 2020 - opg.optica.org
We present a systematic characterization of the optical properties (µ_a and µ_s') of nine
representative ex vivo porcine tissues over a broadband spectrum (650-1100 nm). We …

Solid phantom recipe for diffuse optics in biophotonics applications: a step towards anatomically correct 3D tissue phantoms

SKV Sekar, A Pacheco, P Martella, H Li… - Biomedical optics …, 2019 - opg.optica.org
We present a tissue mimicking optical phantom recipe to create robust well tested solid
phantoms. The recipe consists of black silicone pigment (absorber), silica microspheres …

Rapid determination of the main components of corn based on near-infrared spectroscopy and a BiPLS-PCA-ELM model

L Xu, J Liu, C Wang, Z Li, D Zhang - Applied optics, 2023 - opg.optica.org
To evaluate corn quality quickly, the feasibility of near-infrared spectroscopy (NIRS) coupled
with chemometrics was analyzed to detect the moisture, oil, protein, and starch content in …

The SiPM revolution in time-domain diffuse optics

A Dalla Mora, L Di Sieno, A Behera, P Taroni… - Nuclear Instruments and …, 2020 - Elsevier
Time-domain diffuse optics is a powerful non-invasive, non-ionizing and label-free
technique based on the use of picosecond pulsed laser light to probe highly scattering …

VIS-NIR diffuse reflectance spectroscopy system with self-calibrating fiber-optic probe: study of perturbation resistance

V Perekatova, A Kostyuk, M Kirillin, E Sergeeva… - Diagnostics, 2023 - mdpi.com
We report on the comparative analysis of self-calibrating and single-slope diffuse reflectance
spectroscopy in resistance to different measurement perturbations. We developed an …

Two-layered blood-lipid phantom and method to determine absorption and oxygenation employing changes in moments of DTOFs

A Sudakou, H Wabnitz, A Liemert, M Wolf… - Biomedical Optics …, 2023 - opg.optica.org
Near-infrared spectroscopy (NIRS) is an established technique for measuring tissue oxygen
saturation (StO_2), which is of high clinical value. For tissues that have layered structures, it …

Deep learning-based method to accurately estimate breast tissue optical properties in the presence of the chest wall

M Zhang, S Li, Y Zou, Q Zhu - Journal of Biomedical Optics, 2021 - spiedigitallibrary.org
Significance: In general, image reconstruction methods used in diffuse optical tomography
(DOT) are based on diffusion approximation, and they consider the breast tissue as a …

Estimation of porcine pancreas optical properties in the 600–1100 nm wavelength range for light-based therapies

P Lanka, L Bianchi, A Farina, M De Landro, A Pifferi… - Scientific Reports, 2022 - nature.com
This work reports the optical properties of porcine pancreatic tissue in the broad wavelength
range of 600–1100 nm. Absorption and reduced scattering coefficients (µ a and µ s′) of the …