Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …

Bacteriophages (phages) are viruses that infect bacteria. The “predator–prey” interactions
are recognized as a potentially effective way to treat infections. Phages, as well as phage …

Antibiotics have the remarkable power to control bacterial infections. Unfortunately,
widespread use, whether regarded as prudent or not, has favored the emergence and …

Endolysins are the lytic products of bacteriophages which play a specific role in the release
of phage progeny by degrading the peptidoglycan of the host bacterium. In the light of …

Endolysins and their derivatives have emerged in recent years as a novel class of
antibacterials, which have now entered the clinical phases. Their rapid mode-of-action and …

Highlights•Endolysins are promising agents for detection and control of foodborne
pathogens.•Cell wall binding domains can be used for specific detection of bacteria in …

The global increase in multidrug resistant (MDR) bacteria has led to phage therapy being
refocused upon. A novel endolysin, LysPA26, containing a lysozyme-like domain, was …

The emergence and spread of antibiotic-resistant bacteria drives the search for novel
classes of antibiotics to replenish our armamentarium against bacterial infections. This is …

Introduction: Phages consist of nucleic acids and proteins that may lose their activity under
different physico-chemical conditions. The production process of phage formulations may …

Objectives Multidrug-resistant (MDR) bacteria are a major public-health concern.
Bacteriophage endolysins (lysins) can be used as novel antimicrobial agents against …