Chemical profile and therapeutic potentials of Xylocarpus moluccensis (Lam.) M. Roem.: A literature-based review

MT Islam, J Sharifi-Rad, M Martorell, ES Ali… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Historically, mangrove plants are among the potential
sources of foods and remedies for humans living in the forests and nearby communities …

Proinflammatory effect of endothelial microparticles is mitochondria mediated and modulated through MAPKAPK2 (MAPK-activated protein kinase 2) leading to …

D Tripathi, B Biswas, A Manhas, A Singh… - … and Vascular Biology, 2019 - Am Heart Assoc
Objective—This study investigates the functional significance of mitochondria present in
endothelial microparticles (EMP) and how MK2 (MAPKAPK2 [MAPK-activated protein kinase …

Platelet-derived extracellular vesicles increase Col8a1 secretion and vascular stiffness in intimal injury

H Bao, ZT Li, LH Xu, TY Su, Y Han, M Bao… - Frontiers in cell and …, 2021 - frontiersin.org
The arterial mechanical microenvironment, including stiffness, is a crucial
pathophysiological feature of vascular remodeling, such as neointimal hyperplasia after …

Systemic insulin resistance and metabolic perturbations in chow fed inducible nitric oxide synthase knockout male mice: Partial reversal by nitrite supplementation

H Aggarwal, P Pathak, P Singh, JR Gayen, K Jagavelu… - Antioxidants, 2020 - mdpi.com
iNOS, an important mediator of inflammation, has emerged as an important metabolic
regulator. There are conflicting observations on the incidence of insulin resistance (IR) due …

Chronic intermittent hypobaric hypoxia ameliorates vascular reactivity through upregulating adiponectin expression of PVAT in metabolic syndrome rats

F Cui, H Mi, Y Guan, Y Zhu, R Wang… - Canadian Journal of …, 2023 - cdnsciencepub.com
Cumulating evidence demonstrated that chronic intermittent hypobaric hypoxia (CIHH) had
beneficial effects on the body. This study investigated the role of perivascular adipose tissue …

Improved metabolic stability in iNOS knockout mice with Lactobacillus supplementation

H Aggarwal, J Gautam, SK Gupta, B Das, Y Kumar… - Nutrition Research, 2024 - Elsevier
Oxidative and nitrosative stress play pivotal roles in normal physiological processes and the
pathogenesis of metabolic disorders. Previous studies from our lab demonstrated insulin …

Standardized fraction of Xylocarpus moluccensis inhibits inflammation by modulating MAPK-NFκB and ROS-HIF1α-PKM2 activation

H Agarwal, SR Sukka, V Singh, M Dikshit… - Inflammation …, 2022 - Springer
Objective Present study investigates the effect of Xylocarpus moluccensis (Lamk.) M. Roem
fruit fraction (CDR) on endotoxemia and explores the underlying mechanisms. Materials and …

Xylocarpus moluccensis fruit fraction rescues cardiac hypertrophy by improving angiogenesis and regulating NF-κB-mediated inflammation

A Manhas, D Goyal, B Biswas, D Tripathi… - Pharmacognosy …, 2022 - phcog.com
Background and Aim: The present study was undertaken to investigate the potential of ethyl
acetate fraction obtained from the fruits of Xylocarpus moluccensis alcoholic extract (CDR …

Serum and cecal metabolic profile of the insulin resistant and dyslipidemic p47phox knockout mice

H Aggarwal, P Pathak, SK Gupta, Y Kumar… - Free Radical …, 2022 - Taylor & Francis
Involvement of NOX-dependent oxidative stress in the pathophysiology of metabolic
disorders as well as in the maintenance of metabolic homeostasis has been demonstrated …

Standardized Xylocarpus moluccensis fruit fraction mitigates collagen-induced arthritis in mice by regulating immune response

P Gupta, A Kumar, S Pal, S Kumar… - Journal of Pharmacy …, 2020 - academic.oup.com
Objective This study was undertaken to evaluate the effect of Xylocarpus moluccensis fruit
fraction (F018) on the pathogenesis of collagen-induced arthritis in mice. Methods Arthritis …