Obesity, adipose tissue and vascular dysfunction
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …
are strongly associated with comorbidities such as hypertension and insulin resistance …
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers: A clinical consensus statement from the European Society of Cardiology …
Obesity is a modifiable cardiovascular risk factor, but adipose tissue (AT) depots in humans
are anatomically, histologically, and functionally heterogeneous. For example, visceral AT is …
are anatomically, histologically, and functionally heterogeneous. For example, visceral AT is …
Perivascular adipose tissue and vascular smooth muscle tone: friends or foes?
Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …
[HTML][HTML] 血管周围脂肪与心血管疾病的研究进展
张文娜， 朱浩， 王晓东 - 南京医科大学学报(自然科学版), 2023 - jnmu.njmu.edu.cn
摘要在人体中, 存在着一种围绕着除脑血管外的所有心血管的脂肪组织, 称为血管周围脂肪(
perivascular adipose tis-sue, PVAT). 近年来, 由于其位置及功能的特殊性, PVAT …
perivascular adipose tis-sue, PVAT). 近年来, 由于其位置及功能的特殊性, PVAT …
Single-cell RNA sequencing and assay for transposase-accessible chromatin using sequencing reveals cellular and molecular dynamics of aortic aging in mice
W Xie, Y Ke, Q You, J Li, L Chen, D Li… - … , and vascular biology, 2022 - Am Heart Assoc
Objective: The impact of vascular aging on cardiovascular diseases has been extensively
studied; however, little is known regarding the cellular and molecular mechanisms …
studied; however, little is known regarding the cellular and molecular mechanisms …
Modulatory effect of intermittent fasting on adipose tissue inflammation: amelioration of cardiovascular dysfunction in early metabolic impairment
Cardiometabolic syndrome (CMS) is a cluster of maladaptive cardiovascular, renal,
thrombotic, inflammatory, and metabolic disorders. It confers a high risk of cardiovascular …
thrombotic, inflammatory, and metabolic disorders. It confers a high risk of cardiovascular …
RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II
Most blood vessels are surrounded by perivascular adipose tissue (PVAT), which is a
unique adipose tissue that plays critical roles in vascular physiology and pathophysiology …
unique adipose tissue that plays critical roles in vascular physiology and pathophysiology …
PIEZO1 mechanoreceptor activation reduces adipogenesis in perivascular adipose tissue preadipocytes
During hypertension, vascular remodeling allows the blood vessel to withstand mechanical
forces induced by high blood pressure (BP). This process is well characterized in the media …
forces induced by high blood pressure (BP). This process is well characterized in the media …
Phenotypic changes in T cell and macrophage subtypes in perivascular adipose tissues precede high-fat diet-induced hypertension
Perivascular adipose tissue (PVAT) may connect adiposity to hypertension because of its
vasoactive functions and proximity to blood vessels. We hypothesized that immune cell …
vasoactive functions and proximity to blood vessels. We hypothesized that immune cell …
EGR1 and KLF4 as Diagnostic Markers for Abdominal Aortic Aneurysm and Associated With Immune Infiltration
C Guo, Z Liu, Y Yu, Z Zhou, K Ma, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Formation and rupture of abdominal aortic aneurysm (AAA) is fatal, and the
pathological processes and molecular mechanisms underlying its formation and …
pathological processes and molecular mechanisms underlying its formation and …