Publisher Summary The genetics of Drosophila provides a number of different approaches
toward initiating the investigation of the areas of biogenic-amine metabolism that have …

Critical developmental control genes sometimes contain" shadow" enhancers that can be
located in remote positions, including the introns of neighboring genes [1]. They nonetheless …

During evolution, several types of sequences pass through genomes. Along with mutations
and internal genetic tinkering, they are a useful source of genetic variability for adaptation …

Expression of the yellow (y) gene of Drosophila melanogaster is controlled by a series of
tissue-specific transcriptional enhancers located in the 5'region and intron of the gene …

Phenotypic variation in mammals is frequently attributed to the action of quantitative trait loci
(QTL) or the environment, but may also be epigenetic in origin. Here we consider a …

The chromosomes of eukaryotes are organized into structurally and functionally discrete
domains. Several DNA elements have been identified that act to separate these chromatin …

Chromatin insulators, or boundary elements, affect promoter-enhancer interactions and
buffer transgenes from position effects. The gypsy insulator of Drosophila is bound by a …

The suppressor of Hairy wing (su (Hw)) protein inhibits the function of transcrtptlonal
enhancers located distally from the promoter with respect to the location of su (Hw)-binding …

Mutations in the suppressor of Hairy‐wing [su (Hw)] locus reverse the phenotype of a
number of tissue‐specific mutations caused by insertion of a gypsy retrotransposon. The su …

DNA sequences involved in the control of the developmental and spatial expression of the
yellow locus of Drosophila were identified by phenotypic analysis of germline transformants …