An overview of gene regulation in bacteria by small RNAs derived from mRNA 3′ ends

F Ponath, J Hör, J Vogel - FEMS microbiology reviews, 2022 - academic.oup.com
Over the past two decades, small noncoding RNAs (sRNAs) that regulate mRNAs by short
base pairing have gone from a curiosity to a major class of post-transcriptional regulators in …

Diversity and versatility in small RNA-mediated regulation in bacterial pathogens

B Felden, Y Augagneur - Frontiers in Microbiology, 2021 - frontiersin.org
Bacterial gene expression is under the control of a large set of molecules acting at multiple
levels. In addition to the transcription factors (TFs) already known to be involved in global …

In vivo RNA interactome profiling reveals 3'UTR-processed small RNA targeting a central regulatory hub

F Liu, Z Chen, S Zhang, K Wu, C Bei, C Wang… - Nature …, 2023 - nature.com
Small noncoding RNAs (sRNAs) are crucial regulators of gene expression in bacteria.
Acting in concert with major RNA chaperones such as Hfq or ProQ, sRNAs base-pair with …

Role of the 5′ end phosphorylation state for small RNA stability and target RNA regulation in bacteria

A Schilder, B Görke - Nucleic Acids Research, 2023 - academic.oup.com
In enteric bacteria, several small RNAs (sRNAs) including MicC employ endoribonuclease
RNase E to stimulate target RNA decay. A current model proposes that interaction of the …

Discovery of the major 15–30 nt mammalian small RNAs, their biogenesis and function

H Lai, N Feng, Q Zhai - Nature Communications, 2023 - nature.com
Abstract Small RNAs (sRNAs) within 15-30 nt such as miRNA, tsRNA, srRNA with 3'-OH
have been identified. However, whether these sRNAs are the major 15-30 nt sRNAs is still …

Transcriptional and post-transcriptional control of the nitrate respiration in bacteria

S Durand, M Guillier - Frontiers in molecular biosciences, 2021 - frontiersin.org
In oxygen (O2) limiting environments, numerous aerobic bacteria have the ability to shift
from aerobic to anaerobic respiration to release energy. This process requires alternative …

Gene autoregulation by 3'UTR-derived bacterial small RNAs

M Hoyos, M Huber, KU Förstner, K Papenfort - Elife, 2020 - elifesciences.org
Negative feedback regulation, that is the ability of a gene to repress its own synthesis, is the
most abundant regulatory motif known to biology. Frequently reported for transcriptional …

RNA interactome of hypervirulent Klebsiella pneumoniae reveals a small RNA inhibitor of capsular mucoviscosity and virulence

K Wu, X Lin, Y Lu, R Dong, H Jiang… - Nature …, 2024 - nature.com
Abstract Hypervirulent Klebsiella pneumoniae (HvKP) is an emerging bacterial pathogen
causing invasive infection in immune-competent humans. The hypervirulence is strongly …

Comparison analysis of microbial agent and different compost material on microbial community and nitrogen transformation genes dynamic changes during pig …

N Liu, Z Liu, K Wang, J Zhao, J Fang, G Liu, H Yao… - Bioresource …, 2024 - Elsevier
This study aimed to assess the impact of microbial agent and different compost material, on
physicochemical parameters dynamic change, nitrogen-transfer gene/bacterial community …

Prediction of novel bacterial small RNAs from RIL-Seq RNA–RNA interaction data

A Bar, L Argaman, Y Altuvia, H Margalit - Frontiers in Microbiology, 2021 - frontiersin.org
The genomic revolution and subsequent advances in large-scale genomic and
transcriptomic technologies highlighted hidden genomic treasures. Among them stand out …