Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

More than half of astronauts returning from long-duration missions on the International
Space Station present with neuro-ocular structural and/or functional changes, including optic …

Key Points Astronauts have recently been discovered to have impaired vision, with a
presentation that resembles syndromes of elevated intracranial pressure on Earth. Gravity …

Importance Exposure to a weightless environment during spaceflight results in a chronic
headward blood and tissue fluid shift compared with the upright posture on Earth, with …

We evaluated postural effects on intracranial pressure (ICP) and cerebral perfusion pressure
[CPP: mean arterial pressure (MAP)− ICP] in neurosurgical patients undergoing 24-h ICP …

Key points During long‐term missions, some astronauts experience structural and functional
changes of the eyes and brain which resemble signs/symptoms experienced by patients …

Purpose To test the hypothesis that normal-tension glaucoma (NTG) is caused by an
increased pressure difference across the lamina cribrosa (LC) related to a low intracranial …

Key points Respiration plays a key role in the circulation of cerebrospinal fluid (CSF) around
the central nervous system. During inspiration increased venous return from the cranium is …

Objective The discovery of a posture‐dependent effect on the difference between intraocular
pressure (IOP) and intracranial pressure (ICP) at the level of lamina cribrosa could have …

Background Reference values and physiological measurements of intracranial pressure
(ICP) are primarily reported in the supine position, while reports of ICP in the vertical position …