Recent developments in isocyanide based multicomponent reactions in applied chemistry
A Dömling - Chemical reviews, 2006 - ACS Publications
Multicomponent reactions (MCRs) are generally defined as reactions where more than two
staring materials react to form a product, incorporating essentially all of the atoms of the …
staring materials react to form a product, incorporating essentially all of the atoms of the …
Asymmetric multicomponent reactions (AMCRs): the new frontier
DJ Ramón, M Yus - Angewandte Chemie International Edition, 2005 - Wiley Online Library
Asymmetric multicomponent reactions involve the preparation of chiral compounds by the
reaction of three or more reagents added simultaneously. This kind of addition and reaction …
reaction of three or more reagents added simultaneously. This kind of addition and reaction …
Multicomponent reactions: advanced tools for sustainable organic synthesis
Sustainable or green chemistry has established firm ground providing essential design
criteria for the development of efficient chemical syntheses of complex, high added value …
criteria for the development of efficient chemical syntheses of complex, high added value …
[HTML][HTML] Metal-mediated post-Ugi transformations for the construction of diverse heterocyclic scaffolds
UK Sharma, N Sharma, DD Vachhani… - Chemical Society …, 2015 - pubs.rsc.org
The Ugi-4CR is by far one of the most successful multicomponent reactions leading to high
structural diversity and molecular complexity. However, the reaction mostly affords a linear …
structural diversity and molecular complexity. However, the reaction mostly affords a linear …
[HTML][HTML] Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics
G Koopmanschap, E Ruijter… - Beilstein Journal of …, 2014 - beilstein-journals.org
In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has
received much attention. This because they have shown in many cases enhanced …
received much attention. This because they have shown in many cases enhanced …
Neue Entwicklungen in der asymmetrischen Mehrkomponenten‐Reaktion
DJ Ramón, M Yus - Angewandte Chemie, 2005 - Wiley Online Library
Abstract Unter der asymmetrischen Mehrkomponenten‐Reaktion versteht man die Synthese
von chiralen Verbindungen aus drei oder mehr gleichzeitig zusammengegebenen …
von chiralen Verbindungen aus drei oder mehr gleichzeitig zusammengegebenen …
Applications of multicomponent reactions for the synthesis of diverse heterocyclic scaffolds
JD Sunderhaus, C Dockendorff, SF Martin - Organic letters, 2007 - ACS Publications
A four-component coupling process involving sequential reactions of aldehydes, primary
amines, acid chlorides, and nucleophiles has been developed to prepare multifunctional …
amines, acid chlorides, and nucleophiles has been developed to prepare multifunctional …
Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry
C Hulme, J Dietrich - Molecular diversity, 2009 - Springer
This review details a now established area within the isonitrile multi-component reaction
(IMCR) field of study, namely employing bi-functional reagents in the Ugi reaction for the …
(IMCR) field of study, namely employing bi-functional reagents in the Ugi reaction for the …
Ugi-post functionalization, from a single set of Ugi-adducts to two distinct heterocycles by microwave-assisted palladium-catalyzed cyclizations: tuning the reaction …
W Erb, L Neuville, J Zhu - The Journal of organic chemistry, 2009 - ACS Publications
Linear amides 4, prepared in one step by the Ugi four-component reaction, were converted
to 3, 4-dihydroquinoxalin-3-ones (5) or to 2-(2-oxoindolin-1-yl) acetamides (6) dependent on …
to 3, 4-dihydroquinoxalin-3-ones (5) or to 2-(2-oxoindolin-1-yl) acetamides (6) dependent on …
Concise construction of novel bridged bicyclic lactams by sequenced Ugi/RCM/Heck reactions
TP Ribelin, AS Judd, I Akritopoulou-Zanze… - Organic …, 2007 - ACS Publications
Herein we report a concise protocol for the diastereoselective synthesis of novel bridged
bicyclic lactams from commercially available components by the sequence of Ugi, ring …
bicyclic lactams from commercially available components by the sequence of Ugi, ring …