During tissue development, stem and progenitor cells form functional tissue with high
cellular diversity and intricate micro‐and macro‐architecture. Current approaches have …

The level of muscle development in livestock directly affects the production efficiency of
livestock, and the contents of intramuscular fat (IMF) is an important factor that affects meat …

Nerve tissue engineering is an important strategy for the treatment of brain injuries.
Mesenchymal stem cell (MSC) transplantation has been proven to be able to promote repair …

A characteristic spatial distribution of the main chromatin fractions is observed in most
mammalian cell nuclei, with euchromatin localized in the interior and heterochromatin at the …

Proper expression of the PPARG gene, which encodes a key transcription factor of
adipogenesis, is indispensable in the formation of mature adipocytes. The positioning of a …

Three-dimensional culture systems and suitable substrates topographies demonstrated to
drive stem cell fate in vitro by mechanical conditioning. For example, the Nichoid 3D scaffold …

The normal course of DNA methylation depends on the correct functioning of the DNA
methylation machinery, which include DNA methyltransferase enzymes (DNMTs) and methyl …

The full understanding of molecular mechanisms of cell differentiation requires a holistic
view. Here we combine label-free FTIR and Raman hyperspectral imaging with data mining …

High frequency (HF) mechanical vibration appears beneficial for in vitro osteogenesis of
mesenchymal stem cells (MSCs). However, the current mechanobiological understanding of …

Adipogenesis involves complex changes in gene expression, morphology, and cytoskeletal
organization. However, the quantitative analysis of live cell images to identify their stages …