[HTML][HTML] High-resolution CMOS-based biosensor for assessing hippocampal circuit dynamics in experience-dependent plasticity

BA Emery, X Hu, S Khanzada, G Kempermann… - Biosensors and …, 2023 - Elsevier
Experiential richness creates tissue-level changes and synaptic plasticity as patterns
emerge from rhythmic spatiotemporal activity of large interconnected neuronal assemblies …

Assessment of chemotherapeutic effects on cancer cells using adhesion noise spectroscopy

M Ell, MT Bui, S Kigili, G Zeck… - … in Bioengineering and …, 2024 - frontiersin.org
With cancer as one of the leading causes of death worldwide, there is a need for the
development of accurate, cost-effective, easy-to-use, and fast drug-testing assays. While the …

Pharmacologically and electrically-induced network-wide activation of olfactory bulb with large-scale biosensor

L Rossi, BA Emery, S Khanzada, X Hu… - 2023 IEEE BioSensors …, 2023 - ieeexplore.ieee.org
The olfactory bulb is a multi-layered structure that dynamically tunes high-dimensional
olfactory information from the olfactory epithelium and conveys spatiotemporal codes to …

DENOISING: Dynamic enhancement and noise overcoming in multimodal neural observations via high-density CMOS-based biosensors

X Hu, BA Emery, S Khanzada, H Amin - Frontiers in Bioengineering …, 2024 - frontiersin.org
Large-scale multimodal neural recordings on high-density biosensing microelectrode arrays
(HD-MEAs) offer unprecedented insights into the dynamic interactions and connectivity …

Recording network-based synaptic transmission and LTP in the hippocampal network on a large-scale biosensor

BA Emery, S Khanzada, X Hu, L Rossi… - 2023 IEEE …, 2023 - ieeexplore.ieee.org
The process of learning and memory formation in the hippocampus is a complex
phenomenon involving changes in synaptic efficiency that shape the connections between …

Bottom-up neurogenic-inspired computational model

E Altuntac, X Hu, BA Emery, S Khanzada… - 2023 IEEE …, 2023 - ieeexplore.ieee.org
In this study, we explore computationally the role of the dentate gyrus (DG) in the
hippocampus, particularly its significant contribution to the neurogenic process in the adult …

MEA-seqX: High-resolution Profiling of Large-scale Electrophysiological and Transcriptional Network Dynamics

BA Emery, X Hu, D Kluetsch, S Khanzada, L Larsson… - bioRxiv, 2024 - biorxiv.org
Concepts of brain function imply congruence and mutual causal influence between
molecular events and neuronal activity. Decoding entangled information from concurrent …

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

BA Emery, S Khanzada, X Hu, D Klütsch… - JoVE (Journal of …, 2024 - jove.com
Large-scale neuronal networks and their complex distributed microcircuits are essential to
generate perception, cognition, and behavior that emerge from patterns of spatiotemporal …

Mapping Large-scale Spatiotemporal Dynamics of Synaptic Plasticity and LTP for Memory Encoding in the Hippocampal Network

S Khanzada, X Hu, BA Emery, W Sredniawa… - bioRxiv, 2024 - biorxiv.org
Understanding memory formation requires elucidating the intricate dynamics of neuronal
networks in the hippocampus, where information is encoded and processed through specific …

[PDF][PDF] Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array.

BA Emery, S Khanzada, X Hu, D Klütsch, H Amin - 2024 - researchgate.net
Large-scale neuronal networks and their complex distributed microcircuits are essential to
generate perception, cognition, and behavior that emerge from patterns of spatiotemporal …