Metal-catalyzed C–H functionalization involving isocyanides

B Song, B Xu - Chemical Society Reviews, 2017 - pubs.rsc.org
Isocyanides have a broad range of applications in multicomponent reactions such as
Passerini and Ugi processes. Recent advances in metal catalysis have tremendously …

Sustainable metal catalysis in CH activation

NV Tzouras, IK Stamatopoulos, AT Papastavrou… - Coordination Chemistry …, 2017 - Elsevier
The omnipresence of Csingle bondH bonds in organic compounds renders them highly
attractive targets for the installation of functional groups towards the construction of valuable …

meta-Selective C–H bond alkylation with secondary alkyl halides

N Hofmann, L Ackermann - Journal of the American Chemical …, 2013 - ACS Publications
Ruthenium catalysts enabled C–H bond functionalizations on arenes with challenging
secondary alkyl halides. Particularly, ruthenium (II) biscarboxylate complexes proved to be …

Synthesis, characterization, catalytic activity, and DFT calculations of Zn (II) hydrazone complexes

TT Adejumo, NV Tzouras, LP Zorba, D Radanović… - Molecules, 2020 - mdpi.com
Two new Zn (II) complexes with tridentate hydrazone-based ligands (condensation products
of 2-acetylthiazole) were synthesized and characterized by infrared (IR) and nuclear …

Beyond Friedel and Crafts: innate alkylation of C− H bonds in arenes

G Evano, C Theunissen - Angewandte Chemie International …, 2019 - Wiley Online Library
Alkylated arenes are ubiquitous molecules and building blocks commonly utilized in most
areas of science. Despite its apparent simplicity, the regioselective alkylation of arenes is …

General α‐amino 1, 3, 4‐oxadiazole synthesis via late‐stage reductive functionalization of tertiary amides and lactams

D Matheau‐Raven, DJ Dixon - … Chemie International Edition, 2021 - Wiley Online Library
An iridium‐catalyzed reductive three‐component coupling reaction for the synthesis of
medicinally relevant α‐amino 1, 3, 4‐oxadiazoles from abundant tertiary amides or lactams …

Zn-Catalyzed Multicomponent KA2 Coupling: One-Pot Assembly of Propargylamines Bearing Tetrasubstituted Carbon Centers

NV Tzouras, SP Neofotistos, GC Vougioukalakis - ACS omega, 2019 - ACS Publications
Tetrasubstituted propargylamines comprise a unique class of highly useful compounds,
which can be accessed through the multicomponent coupling between ketones, amines …

Silver-catalyzed C2-selective direct alkylation of heteroarenes with tertiary cycloalkanols

SC Lu, HS Li, S Xu, GY Duan - Organic & Biomolecular Chemistry, 2017 - pubs.rsc.org
A silver-catalyzed regioselective C2-alkylation of heteroarenes with tertiary cycloalkanols
under radical conditions was developed. This tandem process, which includes selective C …

Microwave‐Assisted Organic Synthesis: Overview of Recent Applications

N Sharma, UK Sharma… - Green techniques for …, 2018 - Wiley Online Library
Microwave‐assisted organic synthesis (MAOS) is based on the efficient heat transfer
achieved by dielectric heating, which, in turn, is mainly dependent on the ability of the …

Manganese‐Catalyzed Multicomponent Synthesis of Tetrasubstituted Propargylamines: System Development and Theoretical Study

SP Neofotistos, NV Tzouras, M Pauze… - Advanced Synthesis …, 2020 - Wiley Online Library
Herein, we report a catalytic system based on the earth‐abundant manganese for the
ketone, amine, alkyne (KA2) reaction. The efficiency of manganese manifests at relatively …