Iron overload as a high risk factor for microgravity-induced bone loss

X Chen, J Yang, D Dong, H Lv, B Zhao, Y Xue… - Acta Astronautica, 2019 - Elsevier
Exposure to microgravity during long-term habitation in space results in numerous
physiological alterations in the human body. Among them, reduction in bone mineral density …

A comparison of exercise interventions from bed rest studies for the prevention of musculoskeletal loss

NN Konda, RS Karri, A Winnard, M Nasser, S Evetts… - npj …, 2019 - nature.com
Musculoskeletal loss in actual or simulated microgravity occurs at a high rate. Bed rest
studies are a reliable ground-based spaceflight analogue that allow for direct comparison of …

Simulated galactic cosmic rays modify mitochondrial metabolism in osteoclasts, increase osteoclastogenesis and cause trabecular bone loss in mice

HN Kim, KK Richardson, KJ Krager, W Ling… - International Journal of …, 2021 - mdpi.com
Space is a high-stress environment. One major risk factor for the astronauts when they leave
the Earth's magnetic field is exposure to ionizing radiation from galactic cosmic rays (GCR) …

DERE-Net: A dual-encoder residual enhanced U-Net for muscle fiber segmentation of H&E images

G Du, P Zhang, J Guo, X Zhou, G Kan, J Jia… - … Signal Processing and …, 2024 - Elsevier
Accurate segmentation of hematoxylin-eosin (H&E) muscle fiber images is crucial for the
diagnosis of weightless muscle atrophy. However, uneven contrast, blurred fiber boundaries …

Effects of treadmill with different intensities on bone quality and muscle properties in adult rats

Z Liu, J Gao, H Gong - Biomedical engineering online, 2019 - Springer
Background Bone is a dynamically hierarchical material that can be divided into length
scales of several orders of magnitude. Exercise can cause bone deformation, which in turn …

Knee muscle force estimating model using machine learning approach

A Sohane, R Agarwal - The Computer Journal, 2022 - academic.oup.com
Various simulation type tools and conventional algorithms are being used to determine knee
muscle forces of human during dynamic movement. These all may be good for clinical uses …

Exploring Radiomics Features Based on H&E Images as Potential Biomarkers for Evaluating Muscle Atrophy: A Preliminary Study

G Du, P Zhang, J Guo, X Zhou, G Kan, J Jia… - Journal of Imaging …, 2024 - Springer
Radiomics features have been widely used as novel biomarkers in the diagnosis of various
diseases, but whether radiomics features derived from hematoxylin and eosin (H&E) images …

Роль стимуляции рецепторов опоры в локомоторных тренировках для профилактики гипогравитационных нарушений

ЕВ Фомина, НЮ Лысова, АО Савинкина… - Физиология …, 2021 - elibrary.ru
Анализ времени стимуляции рецепторов опоры в локомоторной тренировке выполнен
индивидуально для 13 космонавтов за каждые сутки длительного космического полета …

Role of Support Receptor Stimulation in Locomotor Training for the Prevention of Hypogravitational Disorders

EV Fomina, NY Lysova, AO Savinkina, RY Zhedyaev… - Human Physiology, 2021 - Springer
The time of stimulation of support receptors in locomotor training was analyzed individually
for 13 cosmonauts for each day of a long-term space flight. The time of support receptors …

[PDF][PDF] Northumbria Research Link

E Boudreau, N Caplan, D Gradwell, R Velho - nrl.northumbria.ac.uk
Space exploration programmes anticipate that human missions to Mars will happen within
the first half of this century. 1, 2 However, one major obstacle in the future of these missions …