Medetomidine is a relatively new sedative analgesic drug that is approved for use in dogs in
Canada. It is the most potent α 2-adrenoreceptor available for clinical use in veterinary …

Medetomidine is a relatively new sedative analgesic in dogs and cats but some precautions
are required when using it. It is a potent α2-adrenoceptor agonist and stimulates receptors …

The clinical effects and pharmacokinetics of medetomidine (MED) and its enanti‐omers,
dexmedetomidine (DEX) and levomedetomidine (LEVO) were compared in a group of six …

Alpha-2 agonists are the only single class of anesthetic drugs that induce reliable, dose-
dependent sedation, analgesia, and muscle relaxation in dogs and cats. Used at low doses …

This article discusses the use of the alpha 2 agonists in the dog and cat. A review of alpha 2
adrenoceptor activity is presented. The alpha 2 agonists xylazine and medetomidine are …

Objective—To evaluate the cardiovascular effects of the α 2-adrenergic receptor agonist
medetomidine hydrochloride in clinically normal cats. Animals—7 clinically normal cats …

Medetomidine and xylazine are alpha 2 adrenoceptor agonists which are used as sedatives
and premedicants in small animals. However, bradycardia is a side effect and the use of …

Objective—To compare sedative, analgesic, and cardiopulmonary effects after IV
administration of medetomidine (20 µg/kg), medetomidine-hydromorphone (20 µg of …

Objective—To determine the cardiorespiratory effects of preemptive atropine administration
in dogs sedated with medetomidine. Design—Randomized crossover trial. Animals—12 …

Objective—To evaluate the effects of medetomidine on dynamic left ventricular outflow tract
(LVOT) obstruction in cats with left ventricular hypertrophy. Design—Clinical trial. Animals …