Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …
were first elucidated in 1994, and by 2001, substantial progress had been made in …
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
M Cargnello, PP Roux - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
The mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs by
relaying extracellular signals to intracellular responses. In mammals, there are more than a …
relaying extracellular signals to intracellular responses. In mammals, there are more than a …
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
Conserved signaling pathways that activate the mitogen-activated protein kinases (MAPKs)
are involved in relaying extracellular stimulations to intracellular responses. The MAPKs …
are involved in relaying extracellular stimulations to intracellular responses. The MAPKs …
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JM Kyriakis, J Avruch - Physiological reviews, 2001 - journals.physiology.org
The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
Functional roles of p38 mitogen‐activated protein kinase in macrophage‐mediated inflammatory responses
Inflammation is a natural host defensive process that is largely regulated by macrophages
during the innate immune response. Mitogen‐activated protein kinases (MAPKs) are proline …
during the innate immune response. Mitogen‐activated protein kinases (MAPKs) are proline …
Hydrogen sulfide is an endogenous stimulator of angiogenesis
A Papapetropoulos, A Pyriochou… - Proceedings of the …, 2009 - National Acad Sciences
The goal of the current study was to investigate the role of exogenous and endogenous
hydrogen sulfide (H2S) on neovascularization and wound healing in vitro and in vivo …
hydrogen sulfide (H2S) on neovascularization and wound healing in vitro and in vivo …
The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions
Y Keshet, R Seger - MAP Kinase Signaling Protocols: Second Edition, 2010 - Springer
Sequential activation of kinases within the mitogen-activated protein (MAP) kinase (MAPK)
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
Activation and signaling of the p38 MAP kinase pathway
T Zarubin, J Han - Cell research, 2005 - nature.com
The family members of the mitogen-activated protein (MAP) kinases mediate a wide variety
of cellular behaviors in response to extracellular stimuli. One of the four main sub-groups …
of cellular behaviors in response to extracellular stimuli. One of the four main sub-groups …
CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals
AJ Shaywitz, ME Greenberg - Annual review of biochemistry, 1999 - annualreviews.org
▪ Abstract Extracellular stimuli elicit changes in gene expression in target cells by activating
intracellular protein kinase cascades that phosphorylate transcription factors within the …
intracellular protein kinase cascades that phosphorylate transcription factors within the …
The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions
S Yoon, R Seger - Growth factors, 2006 - Taylor & Francis
The extracellular signal-regulated kinase (ERK) cascade is a central pathway that transmits
signals from many extracellular agents to regulate cellular processes such as proliferation …
signals from many extracellular agents to regulate cellular processes such as proliferation …