The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …

The mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs by
relaying extracellular signals to intracellular responses. In mammals, there are more than a …

Conserved signaling pathways that activate the mitogen-activated protein kinases (MAPKs)
are involved in relaying extracellular stimulations to intracellular responses. The MAPKs …

The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …

Inflammation is a natural host defensive process that is largely regulated by macrophages
during the innate immune response. Mitogen‐activated protein kinases (MAPKs) are proline …

The goal of the current study was to investigate the role of exogenous and endogenous
hydrogen sulfide (H2S) on neovascularization and wound healing in vitro and in vivo …

Sequential activation of kinases within the mitogen-activated protein (MAP) kinase (MAPK)
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …

The family members of the mitogen-activated protein (MAP) kinases mediate a wide variety
of cellular behaviors in response to extracellular stimuli. One of the four main sub-groups …

▪ Abstract Extracellular stimuli elicit changes in gene expression in target cells by activating
intracellular protein kinase cascades that phosphorylate transcription factors within the …

The extracellular signal-regulated kinase (ERK) cascade is a central pathway that transmits
signals from many extracellular agents to regulate cellular processes such as proliferation …