Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …
highly engage into research on alternative strategies to the traditional small molecule …
Activity and mechanism of action of antifungal peptides from microorganisms: a review
T Li, L Li, F Du, L Sun, J Shi, M Long, Z Chen - Molecules, 2021 - mdpi.com
Harmful fungi in nature not only cause diseases in plants, but also fungal infection and
poisoning when people and animals eat food derived from crops contaminated with them …
poisoning when people and animals eat food derived from crops contaminated with them …
Food applications of liposome-encapsulated antimicrobial peptides
Antimicrobial peptides have been extensively examined as potential biopreservatives in
hurdle technology. However, stability issues like proteolytic degradation and the potential …
hurdle technology. However, stability issues like proteolytic degradation and the potential …
Antimicrobial peptides and induced membrane curvature: Geometry, coordination chemistry, and molecular engineering
NW Schmidt, GCL Wong - Current Opinion in Solid State and Materials …, 2013 - Elsevier
Short cationic, amphipathic antimicrobial peptides are multi-functional molecules that have
roles in host defense as direct microbicides and modulators of the immune response. While …
roles in host defense as direct microbicides and modulators of the immune response. While …
Toxicity of bovicin HC5 against mammalian cell lines and the role of cholesterol in bacteriocin activity
AD Paiva, MD de Oliveira, SO de Paula… - …, 2012 - microbiologyresearch.org
Bacteriocins are ribosomally synthesized antimicrobial peptides produced by Bacteria and
some Archaea. The assessment of the toxic potential of antimicrobial peptides is important in …
some Archaea. The assessment of the toxic potential of antimicrobial peptides is important in …
Rational design of stapled antimicrobial peptides
YH You, HY Liu, YZ Zhu, H Zheng - Amino Acids, 2023 - Springer
The global increase in antimicrobial drug resistance has dramatically reduced the
effectiveness of traditional antibiotics. Structurally diverse antibiotics are urgently needed to …
effectiveness of traditional antibiotics. Structurally diverse antibiotics are urgently needed to …
Nanostructures as promising tools for delivery of antimicrobial peptides
A Brandelli - Mini reviews in medicinal chemistry, 2012 - ingentaconnect.com
Antimicrobial peptides have been extensively investigated for their potential applications as
therapeutics and food biopreservatives. The antimicrobial activity may be impaired by the …
therapeutics and food biopreservatives. The antimicrobial activity may be impaired by the …
Does cholesterol play a role in the bacterial selectivity of antimicrobial peptides?
JR Brender, AJ McHenry, A Ramamoorthy - Frontiers in immunology, 2012 - frontiersin.org
(Figure 1A). Cholesterol has been shown to protect human erythrocytes from attack by
magainin 2 (Matsuzaki et al., 1995b). Similar studies on model membranes have …
magainin 2 (Matsuzaki et al., 1995b). Similar studies on model membranes have …
Selectivity of antimicrobial peptides: a complex interplay of multiple equilibria
S Bobone, L Stella - Antimicrobial Peptides: Basics for Clinical Application, 2019 - Springer
Antimicrobial peptides (AMPs) attack bacterial membranes selectively, killing microbes at
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
concentrations that cause no toxicity to the host cells. This selectivity is not due to interaction …
The structural and topological analysis of membrane-associated polypeptides by oriented solid-state NMR spectroscopy: established concepts and novel …
B Bechinger, JM Resende, C Aisenbrey - Biophysical chemistry, 2011 - Elsevier
Solid-state NMR spectroscopy is a powerful technique for the investigation of membrane-
associated peptides and proteins as well as their interactions with lipids, and a variety of …
associated peptides and proteins as well as their interactions with lipids, and a variety of …