Feature attributions based on the Shapley value are popular for explaining machine
learning models. However, their estimation is complex from both theoretical and …

Background The ongoing pandemic is having a collateral health effect on delivery of
surgical care to millions of patients. Very little is known about pandemic management and …

Over the past decade there has been an increasing reliance on strong opioids to treat acute
and chronic pain, which has been associated with a rising epidemic of prescription opioid …

This review provides an overview of the clinical issue of poorly controlled postoperative pain
and therapeutic approaches that may help to address this common unresolved health-care …

The Lancet Commission on Global Surgery1 identified that 313 million surgical procedures
are performed worldwide each year. Little is known about the quality of surgery globally …

Background This study aimed to evaluate anxiety and pain following perioperative music
interventions compared with control conditions in adult patients. Methods Eleven electronic …

Background During general anaesthesia for noncardiac surgery, there remain knowledge
gaps regarding the effect of goal-directed haemodynamic therapy on patient-centred …

Trauma experienced during surgery can contribute to the development of a systemic
inflammatory response that can cause multi-organ dysfunction or even failure. Post-surgical …

Postoperative cognitive dysfunction (POCD) is a common neurological complication
following surgery and general anesthesia, especially in elderly patients. Severe cases delay …

Background: Both human health and the health systems we depend on are increasingly
threatened by a range of environmental crises, including climate change. Paradoxically …