The growth inhibitory and apoptotic effects of umbelliprenin in a mouse model of systemic candidiasis

M Rashidi, A Bazi, A Ahmadzadeh… - Journal of Applied …, 2023 - academic.oup.com
Aims Umbelliprenin has shown promising biological activities, including immunoregulatory,
anti-inflammatory, and anti-cancer effects. The present study investigated the growth …

Early production of proinflammatory cytokines in response to Scedosporium apiospermum during murine pulmonary infection

CE Luna-Rodríguez, GM González… - Microbial …, 2022 - Elsevier
Scedosporium apiospermum is an opportunistic pathogen that can cause pulmonary
infections in both immunosuppressive and immunocompetent patients. Cytokines are …

Dissemination of Candida auris to deep organs in neonatal murine invasive candidiasis

O Flores-Maldonado, GM González, A Andrade… - Microbial …, 2021 - Elsevier
Candida auris is an emerging multidrug resistant fungal pathogen, which represents a major
challenge for newborns systemic infections worldwide. Management of C. auris infections is …

[HTML][HTML] Candida albicans causes brain regional invasion and necrosis, and activation of microglia during lethal neonatal neurocandidiasis

O Flores-Maldonado, GM González… - Microbes and …, 2023 - Elsevier
Neurocandidiasis is a fungal infection that primarily affects neonates, which is associated
with 70% case fatality rates, while pediatric patients who survive infection often have long …

Genome-wide association study identifies genes and networks that influence innate immune response in an age-specific manner in Drosophila melanogaster

S Campbell, I Gudino, M Rhee, J Leips - 2022 - researchsquare.com
Background The innate immune response is an evolutionarily conserved process that is
essential for survival in multicellular organisms. As individuals age, immune functions …

The Development of a Human-Relevant Pre-Clinical Mouse Model of Disseminated Cerebral Aspergillosis and Defining the Subsequent Neuroimmune Response

BN Sullivan - 2022 - search.proquest.com
Exposure of immunosuppressed individuals to the opportunistic fungal pathogen Aspergillus
(A.) fumigatus may result in invasive pulmonary aspergillosis (IPA), which could lead to the …