Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with …

C Lite, A Guru, M Juliet… - Environmental …, 2022 - Wiley Online Library
Parabens are synthetic antimicrobial compounds used as a preservative for extending the
shelf life of food, pharmaceutical and cosmetic products. The alkyl chain length of the …

Exploration of procyanidin C1 from Uncaria laevigata as a green corrosion inhibitor in industry: Electrochemical assessment, theoretical simulation, and environmental …

L Huang, Y Liu, ZM Wang, WY Lu, XY Li, HJ Li… - Separation and …, 2023 - Elsevier
Traditional corrosion inhibitors have made great contributions to equipment cleaning, metal
industry and oil well pipelines, but also cause serious environmental pollution. Therefore …

Pro-inflammatory cytokine molecules from Boswellia serrate suppresses lipopolysaccharides induced inflammation demonstrated in an in-vivo zebrafish larval model

NSS Siddhu, A Guru, RC Satish Kumar… - Molecular Biology …, 2022 - Springer
Background Boswellia serrate is an ancient and highly valued ayurvedic herb. Its extracts
have been used in medicine for centuries to treat a wide variety of chronic inflammatory …

Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection

A Guru, G Sudhakaran, M Velayutham… - … and Physiology Part C …, 2022 - Elsevier
This study investigates the therapeutic activity of daidzein, an isoflavone that occurs
naturally in plants and herbs, against gentamicin-induced nephrotoxicity in Madin-Darby …

Protective effect of morin by targeting mitochondrial reactive oxygen species induced by hydrogen peroxide demonstrated at a molecular level in MDCK epithelial cells

PK Issac, M Velayutham, A Guru, G Sudhakaran… - Molecular Biology …, 2022 - Springer
Background The development of diabetic nephropathy is aided by the presence of oxidative
stress. Morin, a natural flavonoid molecule, has been shown to have antioxidant and anti …

Copper sulfate induced toxicological impact on in-vivo zebrafish larval model protected due to acacetin via anti-inflammatory and glutathione redox mechanism

M Singh, A Guru, G Sudhakaran… - … and Physiology Part C …, 2022 - Elsevier
Copper sulfate (CuSO 4) as industrial effluent is intentionally or unintentionally released into
water bodies and accumulates in the fish. Because of its numerous applications, CuSO 4 …

Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from …

A Guru, J Arockiaraj - Journal of Biochemical and Molecular …, 2023 - Wiley Online Library
Humans are exposed to obesity causing Bisphenol A in various ways, especially through
diet and food containers. Bioactive peptides are already reported to have antioxidant …

Potential of oligonucleotide-and protein/peptide-based therapeutics in the management of toxicant/stressor-induced diseases

I Sadeghian, M Akbarpour, FMA Chafjiri… - Naunyn-Schmiedeberg's …, 2024 - Springer
Exposure to toxicants/stressors has been linked to the development of many human
diseases. They could affect various cellular components, such as DNA, proteins, lipids, and …

β-cells regeneration by WL15 of cysteine and glycine-rich protein 2 which reduces alloxan induced β-cell dysfunction and oxidative stress through …

A Guru, G Sudhakaran, MH Almutairi… - Molecular Biology …, 2022 - Springer
Background Pancreatic β-cells are susceptible to oxidative stress, leading to β-cell death
and dysfunction due to enhanced ROS levels and type 2 diabetes. To inhibit the β-cells …

6‐Gingerdione reduces apoptotic conditions in HepG2 cells and inhibits inflammatory cytokine gene expression in alcoholic liver injured zebrafish larvae

A Guru, T Manjunathan, G Sudhakaran… - Chemistry & …, 2023 - Wiley Online Library
Antioxidant natural products and their analogs especially phenolic compounds, exhibit
diverse biological properties, including anti‐inflammatory, antioxidant, and anticancer …