Antiplatelet agents and anticoagulants are a mainstay for the prevention and treatment of
thrombosis. However, despite advances in antithrombotic therapy, a fundamental challenge …

Vitamin K is traditionally connected with blood coagulation, since it is needed for the
posttranslational modification of 7 proteins involved in this cascade. However, it is also …

Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation,
has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant …

Endoplasmic reticulum (ER) is a dynamic organelle orchestrating the folding and post-
translational maturation of almost all membrane proteins and most secreted proteins. These …

It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Vitamin K health benefits have been recently widely shown to extend beyond blood
homeostasis and implicated in chronic low-grade inflammatory diseases such as …

Vitamin K is essential for several physiological processes, such as blood coagulation, in
which it serves as a cofactor for the conversion of peptide-bound glutamate to γ …

Background Pharmacogenetics is not a new subject area but its relevance to drug
prescribing has become clearer in recent years due to developments in gene cloning and …

Vitamin K (VK) is an essential cofactor for the post-translational conversion of peptide-bound
glutamate to γ-carboxyglutamate. The resultant vitamin K–dependent proteins are known or …

Several clinical trials and experimental studies have recently shown that vitamin K (VK)
supplementation benefits the human body. Specifically, VK participates in coagulation and is …