Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants …

Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-
1), declines over time until only low levels can be detected in individuals aged≥ 60 years …

Objectives Sarcopenia, defined as an age-associated loss of skeletal muscle function and
muscle mass, occurs in approximately 6-22% of older adults. This paper presents evidence …

Sarcopenic obesity, a chronic condition, is today a major public health problem with
increasing prevalence worldwide, which is due to progressively aging populations, the …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with
increasing age, being a major component in the development of frailty. Current knowledge …

Background. Lower muscle mass has been correlated with poor physical function; however,
no studies have examined this relationship prospectively. This study aims to investigate …

Context: The risks of testosterone therapy in men remain poorly understood. Objective: The
aim of this study was to conduct a systematic review and meta-analyses of testosterone trials …

Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …