RAB11 small GTPases and associated recycling endosome have been localized to mitotic
spindles and implicated in regulating mitosis. However, the physiological significance of …

Centromere‐associated protein E (CENP‐E) is a kinesin motor protein essential for mitosis
and a new target for anticancer agents with less side effects. To rationally design anticancer …

Synthesis and characterization of 2-styrylchromone derivatives had been done through aldol
condensation between 2-methylchromone and various cinnamaldehyde with modified …

The kinesin-5 family member, Eg5, plays very important role in the mitosis. As a mitotic
protein, Eg5 is the target of various mitotic inhibitors. There are two targeting pockets in the …

Kinesin spindle protein (KSP) is expressed only in cells undergoing cell division, and hence
represents an attractive target for the treatment of cancer. Several KSP inhibitors have been …

Kinesin centromere-associated protein E (CENP-E) has emerged as a potential target for the
development of anticancer drugs due to its involvement in the mitotic progression of the cell …

Kinesin-5 has received considerable attention as a new target for mitosis. Various small-
molecule compounds targeting kinesin-5 have been developed in the last few decades …

Mitotic kinesin Eg5 remains a validated target in antimitotic therapy because of its essential
role in the formation and maintenance of bipolar mitotic spindles. Although numerous Eg5 …

Centromere-associated protein E (CENP-E) plays an essential role in mitosis and is a target
candidate for anticancer drugs. However, it is difficult to design small-molecule inhibitors of …

The transportation and distribution of proteins to specific cellular compartments are vital for
the proper functioning of eukaryotic cells and tissue homeostasis. Rab family of small …