Organocatalytic enantioselective desymmetrisation of achiral or meso compounds is a
powerful strategy for the construction of enantiomerically enriched complex molecules, often …

Owing to their wide reactivity profile, as well as a broad range of biological activity,
organophosphorus compounds play a pivotal role in modern organic chemistry. Recently …

The catalytic enantioselective Michael reaction is the conjugate addition of a resonance‐
stabilized carbanion to an electron‐poor olefin (an αβ‐unsaturated carbonyl compound or a …

Both the 3-fluorooxindole and germinal bisphosphonate structural motifs are prevalent in
bioactive molecules because of their associated biological activities. We describe an …

A set of α-quaternary 3-chloro-1-hydroxyalkylphosphonates, analogues of fosfomycin and
fosfonochlorin, some of which are new compounds, was synthesized. The compounds were …

Asymmetric enamine base activation of carbonyl compounds is a well-known and widely
used strategy for providing functionalization of organic compounds in an efficient way. The …

Quaternary amino acids containing a geminal bisphosphonate moiety have been
synthesized for the first time. The developed two-step reaction sequence utilizes the Michael …

Chiral phosphonates find many applications in medicine, agriculture, materials science and
also in organic synthesis. The rapid growth of asymmetric organocatalysis in the last decade …

An organocatalytic domino reaction consisting of Michael addition/intramolecular alkylation
between α, β‐unsaturated aldehydes and bromophosphonoacetates was developed. Highly …

Asymmetric Michael reaction of 3-homoacyl coumarins and chromone-fused dienes was
developed by employing a chiral squaramide, and a series of coumarin chromone skeletons …