Lipodystrophy: pathophysiology and advances in treatment

CG Fiorenza, SH Chou, CS Mantzoros - Nature Reviews Endocrinology, 2011 - nature.com
Lipodystrophy is a medical condition characterized by complete or partial loss of adipose
tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation …

HIV/AIDS and lipodystrophy: implications for clinical management in resource‐limited settings

JL Finkelstein, P Gala, R Rochford… - African Journal of …, 2015 - journals.lww.com
Introduction: Lipodystrophy is a term used to describe a metabolic complication of fat loss, fat
gain, or a combination of fat loss and gain, which is associated with some antiretroviral …

Position of the American Dietetic Association: nutrition intervention and human immunodeficiency virus infection

C Fields-Gardner - Journal of the American Dietetic Association, 2010 - Elsevier
It is the position of the American Dietetic Association that efforts to optimize nutritional status
through individualized medical nutrition therapy, assurance of food and nutrition security …

Human mesenchymal stem cells as a novel platform for simultaneous evaluation of cytotoxicity and genotoxicity of pharmaceuticals

S Sharma, V Venkatesan, BM Prakhya… - Mutagenesis, 2015 - academic.oup.com
The in vitro micronucleus test is a well-known test for the screening of genotoxic compounds.
However until now, most studies have been performed on either human peripheral …

The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy syndrome: a meta-analysis of randomized trials

SH Sheth, RJ Larson - BMC infectious diseases, 2010 - Springer
Background HIV-associated lipodystrophy syndrome (HALS) is characterized by insulin
resistance, abnormal lipid metabolism and redistribution of body fat. To date, there has been …

[HTML][HTML] Metformin (dimethyl-biguanide) induced DNA damage in mammalian cells

RR Amador, JPF Longo, ZG Lacava… - … and molecular biology, 2012 - SciELO Brasil
Metformin (dimethyl-biguanide) is an insulin-sensitizing agent that lowers fasting plasma-
insulin concentration, wherefore it's wide use for patients with a variety of insulin-resistant …

[PDF][PDF] Metformina: más allá del control glucémico

JA Morantes-Caballero, GA Londoño-Zapata… - Médicas UIS, 2017 - scielo.org.co
Introducción: la metformina es una biguanida que disminuye gluconeogénesis e incrementa
la recaptación de glucosa en los músculos, sin embargo, más allá del glucémico se han …

Obesity in patients with HIV infection: epidemiology, consequences and treatment options

M Papagianni, K Tziomalos - Expert Review of Endocrinology & …, 2016 - Taylor & Francis
Introduction: Even though wasting used to characterize patients with HIV infection prior to
the antiretroviral therapy (ART) era, obesity is becoming increasingly prevalent in this …

Effect of metformin on obesity associated metabolic phenotypes

E Meaney, A Domínguez-Borgua… - Revista mexicana de …, 2016 - medigraphic.com
Background: It is known that there are different metabolic phenotypes associated with
obesity, each of them imposing distinct cardiovascular risk. Metformin is a drug with wide …

[HTML][HTML] Metformin: beyond the glycemic target

JA Morantes-Caballero*, GA Londoño-Zapata*… - Medicas UIS, 2017 - scielo.org.co
Introduction: the metformin is a biguanide which main action is to decrease hepatic glucose
output, primarily by decreasing gluconeogenesis, and increase glucose uptake by muscles …