[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …
an important role in the immune system. The interaction between CXCL13 and its receptor …
Evolution and diversity of immune responses during acute HIV infection
Understanding the earliest immune responses following HIV infection is critical to inform
future vaccines and therapeutics. Here, we review recent prospective human studies in at …
future vaccines and therapeutics. Here, we review recent prospective human studies in at …
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection
Cellular immunity is critical for controlling intracellular pathogens, but individual cellular
dynamics and cell–cell cooperativity in evolving human immune responses remain poorly …
dynamics and cell–cell cooperativity in evolving human immune responses remain poorly …
Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection
Introduction Immunological damage in acute HIV infection (AHI) may predispose to
detrimental clinical sequela. However, studies on the earliest HIV-induced immunological …
detrimental clinical sequela. However, studies on the earliest HIV-induced immunological …
HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies
SI Richardson, AW Chung, H Natarajan… - PLoS …, 2018 - journals.plos.org
While the induction of broadly neutralizing antibodies (bNAbs) is a major goal of HIV
vaccination strategies, there is mounting evidence to suggest that antibodies with Fc effector …
vaccination strategies, there is mounting evidence to suggest that antibodies with Fc effector …
Follicular CD4 T helper cells as a major HIV reservoir compartment: a molecular perspective
Effective antiretroviral therapy (ART) has prevented the progression to AIDS and reduced
HIV-related morbidities and mortality for the majority of infected individuals. However, a …
HIV-related morbidities and mortality for the majority of infected individuals. However, a …
[HTML][HTML] B cell engagement with HIV-1 founder virus envelope predicts development of broadly neutralizing antibodies
Determining which immunological mechanisms contribute to the development of broad
neutralizing antibodies (bNAbs) during HIV-1 infection is a major goal to inform vaccine …
neutralizing antibodies (bNAbs) during HIV-1 infection is a major goal to inform vaccine …
Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?
H Subbaraman, M Schanz, A Trkola - Retrovirology, 2018 - Springer
The elicitation of broadly neutralizing antibodies (bnAbs) is considered crucial for an
effective, preventive HIV-1 vaccine. Led by the discovery of a new generation of potent …
effective, preventive HIV-1 vaccine. Led by the discovery of a new generation of potent …
The role of CXCL13 in antibody responses to HIV-1 infection and vaccination
Y Bekele Feyissa, F Chiodi, Y Sui… - Frontiers in …, 2021 - frontiersin.org
CXCL13 signals through the G protein-coupled chemokine receptor CXCR5 to drive
development of secondary lymphoid tissue as well as B cell and Tfh cell trafficking to …
development of secondary lymphoid tissue as well as B cell and Tfh cell trafficking to …
Cerebrospinal fluid CXCL13 as candidate biomarker of intrathecal immune activation, IgG synthesis and neurocognitive impairment in people with HIV
M Trunfio, L Mighetto, L Napoli, C Atzori… - Journal of Neuroimmune …, 2023 - Springer
Plasma CXC-motif chemokine ligand-13 (CXCL13) has been linked to disease progression
and mortality in people living with HIV (PLWH) and is a candidate target for immune-based …
and mortality in people living with HIV (PLWH) and is a candidate target for immune-based …