Common functions of disordered proteins across evolutionary distant organisms
A Wallmann, C Kesten - International journal of molecular sciences, 2020 - mdpi.com
Intrinsically disordered proteins and regions typically lack a well-defined structure and thus
fall outside the scope of the classic sequence–structure–function relationship. Hence …
fall outside the scope of the classic sequence–structure–function relationship. Hence …
[HTML][HTML] Cisplatin-induced PANDAR-Chemo-EVs contribute to a more aggressive and chemoresistant ovarian cancer phenotype through the SRSF9-SIRT4/SIRT6 …
H Wang, Y Li, Y Wang, X Shang, Z Yan… - Journal of Gynecologic …, 2024 - ncbi.nlm.nih.gov
Objective We previously elucidated that long non-coding RNA Promoter of CDKN1A
Antisense DNA damage Activated RNA (PANDAR) as a p53-dependent oncogene to …
Antisense DNA damage Activated RNA (PANDAR) as a p53-dependent oncogene to …
Insight into the Structural Basis for Dual Nucleic Acid—Recognition by the Scaffold Attachment Factor B2 Protein
SM Korn, J Von Ehr, K Dhamotharan, JN Tants… - International Journal of …, 2023 - mdpi.com
The family of scaffold attachment factor B (SAFB) proteins comprises three members and
was first identified as binders of the nuclear matrix/scaffold. Over the past two decades …
was first identified as binders of the nuclear matrix/scaffold. Over the past two decades …
The molecular and functional interaction between membrane-bound organelles and membrane-less condensates
C Zhou - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
A major recent advance in cell biology is the mechanistic and kinetic understanding of
biogenesis of many membrane-less condensates. As membrane-less condensates and …
biogenesis of many membrane-less condensates. As membrane-less condensates and …
Intrinsically disordered signaling proteins: Essential hub players in the control of stress responses in Saccharomyces cerevisiae
L French-Pacheco, O Rosas-Bringas, L Segovia… - Plos one, 2022 - journals.plos.org
Cells have developed diverse mechanisms to monitor changes in their surroundings. This
allows them to establish effective responses to cope with adverse environments. Some of …
allows them to establish effective responses to cope with adverse environments. Some of …
Image‐based deep learning reveals the responses of human motor neurons to stress and VCP‐related ALS
Aims Although morphological attributes of cells and their substructures are recognised
readouts of physiological or pathophysiological states, these have been relatively …
readouts of physiological or pathophysiological states, these have been relatively …
Image-based deep learning reveals the responses of human motor neurons to stress and ALS
Although morphological attributes of cells and their substructures are recognized readouts of
physiological or pathophysiological states, these have been relatively understudied in …
physiological or pathophysiological states, these have been relatively understudied in …