Prevention and treatment of inflammatory arthritis with traditional Chinese medicine: underlying mechanisms based on cell and molecular targets

W Li, L Yu, W Li, G Ge, Y Ma, L Xiao, Y Qiao… - Ageing Research …, 2023 - Elsevier
Inflammatory arthritis, primarily including rheumatoid arthritis, osteoarthritis and ankylosing
spondylitis, is a group of chronic inflammatory diseases, whose general feature is joint …

Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

S Chen, J Zeng, R Li, Y Zhang, Y Tao, Y Hou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …

[HTML][HTML] Mitochondrion-NLRP3 inflammasome activation in macrophages: A novel mechanism of the anti-inflammatory effect of Notopterygium in rheumatoid arthritis …

X Liu, X Chen, C Zhang, M Huang, H Yu… - Biomedicine & …, 2023 - Elsevier
Objective The mechanism by which Notopterygium (NE) regulates the nucleotide‐binding,
oligomerization domain (NOD)‐like receptor family and pyrin domain-containing 3 (NLRP3) …

Targeting different phenotypes of macrophages: A potential strategy for natural products to treat inflammatory bone and joint diseases

Y Gao, X Xu, X Zhang - Phytomedicine, 2023 - Elsevier
Background Macrophages, a key class of immune cells, have a dual role in inflammatory
responses, switching between anti-inflammatory M2 and pro-inflammatory M1 subtypes …

Water extracts of Tibetan medicine Wuweiganlu attenuates experimental arthritis via inducing macrophage polarization towards the M2 type

Y Wen, S Zhang, X Meng, C Zhao, B Hou, X Zhu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Wuweiganlu (WGL) is a well-known formulation described
in the “Four Medical Scriptures of Tibetan medicine”, which is mainly used for the treatment …

[HTML][HTML] Global scientific trends update on macrophage polarization in rheumatoid arthritis: A bibliometric and visualized analysis from 2000 to 2022

J Yuan, T Feng, Y Guo, K Luo, Q Wu, S Yu, H Zhou - Heliyon, 2023 - cell.com
The goal of this work was to use bibliometric analysis to help guide future research on
macrophage polarization in RA. We looked for studies on macrophage polarization in RA …

[HTML][HTML] Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin

W Lin, Y Song, T Li, J Yan, R Zhang, L Han, X Ba… - Biomedicine & …, 2023 - Elsevier
Background Fibrotic extracellular matrix (ECM) remodeling characterized different types of
pulmonary fibrosis, and its regulation could be a potential shared treatment strategy for …

Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

M Li, F Tian, J Guo, X Li, L Ma, M Jiang… - Frontiers in …, 2023 - frontiersin.org
Arthritis is a common degenerative disease of joints, which has become a public health
problem affecting human health, but its pathogenesis is complex and cannot be eradicated …

Screening bioactive compounds from Fangji Huangqi decoction for treating rheumatoid arthritis via COX-2 magnetic ligand fishing combined with in vivo validation

Y Zhu, A Duan, Q Yu, S Tian, Z Zhou, P Li, D Pan… - Journal of …, 2025 - Elsevier
Abstract Ethnopharmacological relevance Fangji Huangqi Decoction (FHD) is a classical
Chinese compound formula for treating rheumatoid arthritis (RA) with satisfactory effects …

Effect of Salvia miltiorrhiza Bunge extracts on improving the efficacy and reducing the toxicity of Tripterygium wilfordii polyglycosides in the treatment of rheumatoid …

L Zhang, S Jiang, Z Guan, J Huang, Z Yin, G Tan… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Tripterygium wilfordii polyglycosides (TWP), extracted from
the traditional Chinese herb Tripterygium wilfordii, has been widely used in the treatment of …