Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
Clinical updates in adult immune thrombocytopenia
MP Lambert, TB Gernsheimer - Blood, The Journal of the …, 2017 - ashpublications.org
Immune thrombocytopenia (ITP) occurs in 2 to 4/100 000 adults and results in variable
bleeding symptoms and thrombocytopenia. In the last decade, changes in our …
bleeding symptoms and thrombocytopenia. In the last decade, changes in our …
Pathogenesis of immune thrombocytopenia
S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …
response, notably supported by splenic T follicular helper cells, that stimulates the …
Emerging concepts in immune thrombocytopenia
M Swinkels, M Rijkers, J Voorberg… - Frontiers in …, 2018 - frontiersin.org
Immune thrombocytopenia (ITP) is an autoimmune disease defined by low platelet counts
which presents with an increased bleeding risk. Several genetic risk factors (eg …
which presents with an increased bleeding risk. Several genetic risk factors (eg …
A review of romiplostim mechanism of action and clinical applicability
JB Bussel, G Soff, A Balduzzi, N Cooper… - Drug design …, 2021 - Taylor & Francis
Thrombocytopenia results from a variety of conditions, including radiation, chemotherapy,
autoimmune disease, bone marrow disorders, pathologic conditions associated with …
autoimmune disease, bone marrow disorders, pathologic conditions associated with …
Cellular immune dysfunction in immune thrombocytopenia (ITP)
Over the past decades, a wealth of information has been reported about the pathogenic
features of immune thrombocytopenia (ITP). To this day, however, it is unclear whether the …
features of immune thrombocytopenia (ITP). To this day, however, it is unclear whether the …
Immune thrombocytopenic purpura (ITP) associated with vaccinations: a review of reported cases
C Perricone, F Ceccarelli, G Nesher, E Borella… - Immunologic …, 2014 - Springer
Immune thrombocytopenic purpura (ITP) is an autoimmune condition characterized by low
platelet count with mucocutaneous and other bleedings. Clinical manifestations may range …
platelet count with mucocutaneous and other bleedings. Clinical manifestations may range …
The imbalance of Th17/Treg cells is involved in the progression of nonalcoholic fatty liver disease in mice
B He, L Wu, W Xie, Y Shao, J Jiang, Z Zhao, M Yan… - BMC immunology, 2017 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a common, chronic liver disease
worldwide. Recent studies have shown that T helper (Th) 17 and regulatory T (Treg) cells …
worldwide. Recent studies have shown that T helper (Th) 17 and regulatory T (Treg) cells …