Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

The uptake of metal–organic frameworks: A journey into the cell

E Linnane, S Haddad, F Melle, Z Mei… - Chemical Society …, 2022 - pubs.rsc.org
The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …

Amplifying STING activation by cyclic dinucleotide–manganese particles for local and systemic cancer metalloimmunotherapy

X Sun, Y Zhang, J Li, KS Park, K Han, X Zhou… - Nature …, 2021 - nature.com
Nutritional metal ions play critical roles in many important immune processes. Hence, the
effective modulation of metal ions may open up new forms of immunotherapy, termed as …

Postsynthetic modification: an enabling technology for the advancement of metal–organic frameworks

M Kalaj, SM Cohen - ACS Central Science, 2020 - ACS Publications
Metal–organic frameworks (MOFs) are a class of porous materials with immense chemical
tunability derived from their organic and inorganic building blocks. Presynthetic approaches …

A metal–polyphenol‐coordinated nanomedicine for synergistic cascade cancer chemotherapy and chemodynamic therapy

Z Ren, S Sun, R Sun, G Cui, L Hong, B Rao… - Advanced …, 2020 - Wiley Online Library
The clinical application of chemotherapy is impeded by the unsatisfactory efficacy and
severe side effects. Chemodynamic therapy (CDT) has emerged as an efficient strategy for …

Metal–organic framework nanoparticles

S Wang, CM McGuirk, A d'Aquino, JA Mason… - Advanced …, 2018 - Wiley Online Library
Due to their well‐defined 3D architectures, permanent porosity, and diverse chemical
functionalities, metal–organic framework nanoparticles (MOF NPs) are an emerging class of …

Nanoscale metal–organic frameworks for therapeutic, imaging, and sensing applications

K Lu, T Aung, N Guo, R Weichselbaum… - Advanced …, 2018 - Wiley Online Library
Nanotechnology has played an important role in drug delivery and biomedical imaging over
the past two decades. In particular, nanoscale metal–organic frameworks (nMOFs) are …

Stimuli-responsive drug delivery systems triggered by intracellular or subcellular microenvironments

T Sun, C Jiang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Drug delivery systems (DDS) triggered by local microenvironment represents the state-of-art
of nanomedicine design, where the triggering hallmarks at intracellular and subcellular …

Metal complexes in cancer therapy–an update from drug design perspective

U Ndagi, N Mhlongo, ME Soliman - Drug design, development and …, 2017 - Taylor & Francis
In the past, metal-based compounds were widely used in the treatment of disease
conditions, but the lack of clear distinction between the therapeutic and toxic doses was a …

Metal–organic frameworks: a future toolbox for biomedicine?

RF Mendes, F Figueira, JP Leite, L Gales… - Chemical Society …, 2020 - pubs.rsc.org
The present review focuses on the use of Metal–Organic Frameworks,(MOFs) highlighting
the most recent developments in the biological field. This review assesses, in the first …