Dysfunction of motor cortices in Parkinson's disease

HY Chu, Y Smith, WW Lytton, S Grafton… - Cerebral …, 2024 - academic.oup.com
The cerebral cortex has long been thought to be involved in the pathophysiology of motor
symptoms of Parkinson's disease. The impaired cortical function is believed to be a direct …

[HTML][HTML] Adverse and compensatory neurophysiological slowing in Parkinson's disease

AI Wiesman, J da Silva Castanheira, C Degroot… - Progress in …, 2023 - Elsevier
Patients with Parkinson's disease (PD) exhibit multifaceted changes in neurophysiological
brain activity, hypothesized to represent a global cortical slowing effect. Using task-free …

Decreased aperiodic neural activity in Parkinson's disease and dementia with Lewy bodies

Y Rosenblum, T Shiner, N Bregman, N Giladi… - Journal of …, 2023 - Springer
Neural oscillations and signal complexity have been widely studied in neurodegenerative
diseases, whereas aperiodic activity has not been explored yet in those disorders. Here, we …

Cortex-wide topography of 1/f-exponent in Parkinson's disease

P Helson, D Lundqvist, P Svenningsson… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is a progressive and debilitating brain disorder. Besides the
characteristic movement-related symptoms, the disease also causes decline in sensory and …

Resting EEG periodic and aperiodic components predict cognitive decline over 10 years

AJ Finley, DJ Angus, EL Knight… - Journal of …, 2024 - Soc Neuroscience
Measures of intrinsic brain function at rest show promise as predictors of cognitive decline in
humans, including EEG metrics such as individual α peak frequency (IAPF) and the …

[HTML][HTML] Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentials

J Kim, J Lee, E Kim, JH Choi, JC Rah, JW Choi - Neurobiology of Disease, 2022 - Elsevier
Electrophysiological biomarkers reflecting the pathological activities in the basal ganglia are
essential to gain an etiological understanding of Parkinson's disease (PD) and develop a …

the Swedish National Facility for Magnetoencephalography Parkinson's disease dataset

MC Vinding, A Eriksson, I Comarovschii, J Waldthaler… - Scientific Data, 2024 - nature.com
Parkinson's disease (PD) is characterised by a loss of dopamine and dopaminergic cells.
The consequences hereof are widespread network disturbances in brain function. It is an …

Early detection of Parkinson's disease: Systematic analysis of the influence of the eyes on quantitative biomarkers in resting state electroencephalography

G Giménez-Aparisi, E Guijarro-Estelles… - Heliyon, 2023 - cell.com
While resting state electroencephalography (EEG) provides relevant information on
pathological changes in Parkinson's disease, most studies focus on the eyes-closed EEG …

[HTML][HTML] Critical analysis of Parkinson's disease detection using EEG sub-bands and gated recurrent unit

N Khalid, MS Ehsan - … Science and Technology, an International Journal, 2024 - Elsevier
Parkinson's disease, the second most common neurodegenerative disorder in the world. A
progressive disease, which can worsen over time and lead to complications like mild …

A sagittal gradient of pathological and compensatory effects of neurophysiological slowing in Parkinson's disease

AI Wiesman, J da Silva Castanheira, C Degroot… - medRxiv, 2022 - medrxiv.org
Using magnetoencephalographic imaging and extensive clinical and neuropsychological
assessments, we show that patients with Parkinson's disease (PD; N= 79) exhibit a slowing …