[HTML][HTML] Environmental chemicals, breast cancer progression and drug resistance

M Koual, C Tomkiewicz, G Cano-Sancho… - Environmental …, 2020 - Springer
Breast cancer (BC) is one of the most common causes of cancer in the world and the second
leading cause of cancer deaths among women. Mortality is associated mainly with the …

Aryl hydrocarbon receptor and its diverse ligands and functions: an exposome receptor

L Larigot, L Benoit, M Koual… - Annual Review of …, 2022 - annualreviews.org
The aryl hydrocarbon receptor (AhR) is a transcriptional factor that regulates multiple
functions following its activation by a variety of ligands, including xenobiotics, natural …

A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey …

DH Lee, IK Lee, K Song, M Steffes, W Toscano… - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—Low-level exposure to some persistent organic pollutants (POPs) has recently
become a focus because of their possible link with the risk of diabetes. RESEARCH DESIGN …

[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis

V Arsenescu, RI Arsenescu, V King… - Environmental …, 2008 - ehp.niehs.nih.gov
Background Obesity, an inflammatory condition linked to cardiovascular disease, is
associated with expansion of adipose tissue. Highly prevalent coplanar polychlorinated …

[HTML][HTML] Relationship between serum concentrations of persistent organic pollutants and the prevalence of metabolic syndrome among non-diabetic adults: results …

DH Lee, IK Lee, M Porta, M Steffes, DR Jacobs - Diabetologia, 2007 - Springer
Aims/hypothesis We recently reported associations of some persistent organic pollutants
(POPs) with both prevalence of type 2 diabetes and insulin resistance in a US population …

Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly

PM Lind, L Lind - Atherosclerosis, 2011 - Elsevier
BACKGROUND AND OBJECTIVE: Bisphenol A (BPA) levels have previously been
associated with coronary heart disease (CHD). Since CHD is an atherosclerotic disease, we …

[图书][B] The biology of human longevity: Inflammation, nutrition, and aging in the evolution of lifespans

CE Finch - 2010 - books.google.com
Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human
Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes …

Key characteristics of cardiovascular toxicants

L Lind, JA Araujo, A Barchowsky… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: The concept of chemical agents having properties that confer potential hazard
called key characteristics (KCs) was first developed to identify carcinogenic hazards …

Fine particulate matter induces heart defects via AHR/ROS-mediated endoplasmic reticulum stress

M Zhang, J Chen, Y Jiang, T Chen - Chemosphere, 2022 - Elsevier
Accumulating body of evidence indicates that exposure to fine particulate matter (PM 2.5) is
closely associated with congenital heart disease in the offspring, but the underlying …