Diabetes and colorectal cancer risk: a new look at molecular mechanisms and potential role of novel antidiabetic agents

J Vekic, A Zeljkovic, A Stefanovic, RV Giglio… - International Journal of …, 2021 - mdpi.com
Epidemiological data have demonstrated a significant association between the presence of
type 2 diabetes mellitus (T2DM) and the development of colorectal cancer (CRC). Chronic …

Randomised controlled trial of intermittent vs continuous energy restriction during chemotherapy for early breast cancer

M Harvie, M Pegington, SJ Howell, N Bundred… - British Journal of …, 2022 - nature.com
Background Excess adiposity at diagnosis and weight gain during chemotherapy is
associated with tumour recurrence and chemotherapy toxicity. We assessed the efficacy of …

Preclinical-to-clinical anti-cancer drug response prediction and biomarker identification using TINDL

DE Hostallero, L Wei, L Wang, J Cairns… - Genomics, Proteomics …, 2023 - academic.oup.com
Prediction of the response of cancer patients to different treatments and identification of
biomarkers of drug response are two major goals of individualized medicine. Here, we …

[HTML][HTML] Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway

J He, A Yang, X Zhao, Y Liu, S Liu, D Wang - Food Science and Human …, 2021 - Elsevier
The incidence rate of colon cancer ranks the third among malignant tumors worldwide.
Gloeostereum incarnatum (GI), a fungus with homology of medicine and food, has multiple …

KPNA2-associated immune analyses highlight the dysregulation and prognostic effects of GRB2, NRAS, and their RNA-binding proteins in hepatocellular carcinoma

X Zhang, J Zhang, F Gao, S Fan, L Dai… - Frontiers in genetics, 2020 - frontiersin.org
Karyopherin α2 (KPNA2) was reported to be overexpressed and have unfavorable
prognostic effects in many malignancies including hepatocellular carcinoma (HCC) …

Identification of a novel lipid metabolism-related gene signature for predicting colorectal cancer survival

Y Huang, J Zhou, H Zhong, N Xie, FR Zhang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is a common malignant tumor worldwide. Lipid metabolism is a
prerequisite for the growth, proliferation and invasion of cancer cells. However, the lipid …

A deep learning framework for prediction of clinical drug response of cancer patients and identification of drug sensitivity biomarkers using preclinical samples

DE Hostallero, L Wei, L Wang, J Cairns, A Emad - biorxiv, 2021 - biorxiv.org
Background Prediction of the response of cancer patients to different treatments and
identification of biomarkers of drug sensitivity are two major goals of individualized …

Applications of deep learning and graph representation learning in precision cancer medicine

D Hostallero - 2024 - escholarship.mcgill.ca
Computationally designing personalized treatment plans to increase a cancer patient's
chances of recovery using their molecular profiles has been one of the major objectives of …

A Multimodal Strategic Approach to Integrative Oncology

JA Stoff - Asian Journal of Immunology, 2022 - go7publish.com
The term “integrative oncology” can mean particular things to different audiences. For the
purposes of this article, I intend it to mean the simultaneous use of multiple anti-cancer …

[图书][B] Transcriptomics and Metabonomics in Precision Medicine of Inflammatory Bowel Disease: Diagnostics, Phenotypes, and Novel Treatment Strategies

JT Bjerrum - 2023 - healthsciences.ku.dk
Transcriptomics and Metabonomics in Precision Medicine of Inflammatory Bowel Disease:
Diagnostics, Phenotypes, and Novel Treatme Page 1 Transcriptomics and Metabonomics in …