Establishing outcome measures in early knee osteoarthritis

CA Emery, JL Whittaker, A Mahmoudian… - Nature Reviews …, 2019 - nature.com
The classification and monitoring of individuals with early knee osteoarthritis (OA) are
important considerations for the design and evaluation of therapeutic interventions and …

Environmental risk factors for osteoarthritis: The impact on individuals with knee joint injury

DM Werner, YM Golightly, M Tao… - Rheumatic …, 2022 - rheumatic.theclinics.com
Discussion Risk factors for the development and progression of early knee OA can be
broken into two categories: non-modifiable and modifiable (Table 1). Non-modifiable risk …

Gait Mechanics and T1ρ MRI of Tibiofemoral Cartilage 6 Months after ACL Reconstruction.

SJ Pfeiffer, J Spang, D Nissman, D Lalush… - Medicine and science …, 2019 - europepmc.org
Purpose Aberrant walking biomechanics after anterior cruciate ligament reconstruction
(ACLR) are hypothesized to be associated with deleterious changes in knee cartilage. T1ρ …

[HTML][HTML] Bilateral gait six and twelve months post-ACL reconstruction compared to controls

HC Davis-Wilson, SJ Pfeiffer, CD Johnston… - Medicine and science …, 2020 - ncbi.nlm.nih.gov
Purpose To compare gait biomechanics throughout stance phase 6 and 12 months following
unilateral anterior cruciate ligament reconstruction (ACLR) between ACLR and contralateral …

[HTML][HTML] Walking ground reaction force post-ACL reconstruction: analysis of time and symptoms

B Pietrosimone, MK Seeley, C Johnston… - Medicine and science …, 2019 - ncbi.nlm.nih.gov
Purpose: The association between lower-extremity loading and clinically-relevant knee
symptoms at different time points following anterior cruciate ligament reconstruction (ACLR) …

MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis

HF Atkinson, TB Birmingham, RF Moyer… - BMC musculoskeletal …, 2019 - Springer
Background Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly
being proposed as imaging biomarkers potentially capable of detecting biochemical …

Quadriceps weakness associates with greater T1ρ relaxation time in the medial femoral articular cartilage 6 months following anterior cruciate ligament reconstruction

B Pietrosimone, SJ Pfeiffer, MS Harkey… - Knee Surgery, Sports …, 2019 - Springer
Purpose Quadriceps weakness following anterior cruciate ligament reconstruction (ACLR) is
linked to decreased patient-reported function, altered lower extremity biomechanics and …

Hop testing lacks strong association with key outcome variables after primary anterior cruciate ligament reconstruction: a systematic review

JM Losciale, G Bullock, C Cromwell… - … American journal of …, 2020 - journals.sagepub.com
Background: Single-legged hop tests are commonly used assessments in return to sport
(RTS) testing after anterior cruciate ligament reconstruction (ACLR). Although these tests are …

Loading during midstance of gait is associated with magnetic resonance imaging of cartilage composition following anterior cruciate ligament reconstruction

E Bjornsen, TA Schwartz, C Lisee, T Blackburn… - Cartilage, 2022 - journals.sagepub.com
Objective A complex association exists between aberrant gait biomechanics and
posttraumatic knee osteoarthritis (PTOA) development. Previous research has primarily …

Gait biomechanics in individuals meeting sufficient quadriceps strength cutoffs after anterior cruciate ligament reconstruction

B Pietrosimone, HC Davis-Wilson… - Journal of Athletic …, 2021 - meridian.allenpress.com
Context Quadriceps weakness is associated with disability and aberrant gait biomechanics
after anterior cruciate ligament reconstruction (ACLR). Strength-sufficiency cutoff scores …