The nitric oxide pathway plays a critical role in vascular homeostasis. Increased levels of
systemic nitric oxide (NO) are observed in preclinical models of sepsis and endotoxemia …

Mycoplasma hyopneumoniae: is the etiological agent of porcine enzootic pneumonia (EP), a
disease that impacts the swine industry worldwide. Pathogen-induced damage, as well as …

Toddalolactone (TA-8) is a main compound isolated from Toddalia asiatica (L.) Lam., and its
anti-inflammatory activity and anti-inflammatory mechanism are less studied. In the present …

Abstract Interferon-gamma (IFN-γ) is a type II interferon produced primarily by T cells and
natural killer cells. IFN-γ induces the expression of inducible nitric oxide synthase (NOS2) to …

The enzyme nitric oxide synthase 2 or inducible NOS (NOS2), reactive oxygen species
(ROS) and nitric oxide (NO) are important participants in various inflammatory and immune …

Endoplasmic reticulum stress is closely associated with the onset and progression of
inflammatory bowel disease. ERdj5 is an endoplasmic reticulum-resident protein disulfide …

Sepsis, a potentially lethal condition resulting from failure to control the initial infection, is
associated with a dysregulated host defense response to pathogens and their toxins. Sepsis …

Lactobacillus reuteri, a typical intestinal symbiotic bacterium, plays an important role in
maintaining intestinal flora stability and host health. However, the effect of Lactobacillus …

Abstract Ethnopharmacological relevance Corydalis tomentella Franch. is a perennial
cespitose plant commonly used to treat stomachaches as a folk medicine. The C. tomentella …

Toll-like receptors (TLRs) are a family of pattern-recognition receptors involved in innate
immunity. Previous studies have shown that TLR2 inhibition protects the heart from acute …