Thienopyrimidines are widely represented in the literature, mainly due to their structural
relationship with purine base such as adenine and guanine. This current review presents …

This review presents the most elegant and promising set of synthetic routes for the synthesis
of 2‐aminothiophenes by the Gewald reaction. This reaction has applications in several …

A multicomponent synthesis was empolyed for the synthesis of ethyl 2-amino-4, 5, 6, 7-
tetrahydrobenzo [b] thiophene-3-carboxylate 1. An interesting cyclization was obtained …

Background Antibiotic resistance has contributed to the burden of infectious diseases both in
the hospital and community setting, and represents a great threat to public health. Previous …

The discovery of antibacterials is considered one of the greatest medical achievements of all
time. In this work, a combination of three computational analyzes: 3D-QSAR, molecular …

BACKGROUND Plant virus diseases are difficult to prevent and control, causing serious
economic losses to the agricultural production world. To develop new pesticides with …

Antibiotic resistance poses a serious threat to public health, raising the number of diseases
in the community. Recent research has shown that plant-derived phenolic compounds have …

Two series of new tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidines namely 2, 3-
disubstituted derivatives 3a–z and 2, 4-disubstituted ones 6a–c were prepared and tested …

Abstract A series of thieno [2, 3-d] pyrimidine alkyne Mannich base derivatives (7a-e, 8a-e)
and thieno [2, 3-d] pyrimidine 1, 3, 4-oxadiazole derivatives (9a-e, 10a-e) have been …

A new route for the synthesis of quinazolin-2, 4 (1 H, 3 H)-diones and thieno [2, 3-d]
pyrimidine-2, 4 (1 H, 3 H)-diones substituted by pyridyl/quinolinyl moiety in position 3 has …