The topics of verification and validation have increasingly been discussed in the field of
computational biomechanics, and many recent articles have applied these concepts in an …

Finite element modeling is an engineering tool for structural analysis that has been used for
many years to assess the relationship between load transfer and bone morphology and to …

Cellular structures with highly controlled micro-architectures are promising materials for
orthopedic applications that require bone-substituting biomaterials or implants. The …

The prediction of the stress-state and fracture risk induced in bones by various loading
conditions in individual patients using subject-specific finite element models still represents …

Aim of the present study was to evaluate the influence on the global model's accuracy of the
strategy adopted to define the average element Young's modulus in subject-specific finite …

The determination of the mechanical stresses induced in human bones is of great
importance in both research and clinical practice. Since the stresses in bones cannot be …

PURPOSE: Femoral fracture is a common medical problem in osteoporotic individuals. Bone
mineral density (BMD) is the gold standard measure to evaluate fracture risk in vivo …

Background: The mechanical response of patient-specific bone to various load conditions is
of major clinical importance in orthopedics. Herein we enhance the methods presented in …

Standard methods for predicting bone's mechanical response from quantitative computer
tomography (qCT) scans are mainly based on classical h-version finite element methods …

Mechanical stimuli are one of the factors that affect cell proliferation and differentiation in the
process of bone tissue regeneration. Knowledge on the specific deformation sensed by cells …