The management of the central nervous system (CNS) disorders is challenging, due to the
need of drugs to cross the blood‒brain barrier (BBB) and reach the brain. Among the …

Chitosan-based nanomaterials have attracted significant attention in the biomedical field
because of their unique biodegradable, biocompatible, non-toxic, and antimicrobial nature …

The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Chitosan is a natural fiber, chemically cellulose-like biopolymer, which is processed from
chitin. Its use as a natural polymer is getting more attention because it is non-toxic …

Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

This study aims to develop chitosan-coated PLGA nanoparticles intended for nose-to-brain
delivery of carmustine. Formulations were prepared by the double emulsion solvent …

Nose-to-brain drug delivery has been of great interest for the treatment of many central
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …

Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …

Nose to brain drug delivery is considered as a viable option to deliver various therapeutic
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …

Rivastigmine is a drug commonly used in the management of Alzheimer's disease that
shows bioavailability problems. To overcome this, the use of nanosystems, such as …