Cholangiocarcinomas (CCA) are a heterogeneous group of tumors that are classified as
intrahepatic, perihilar, or distal according to the anatomic location within the biliary tract …

The use of next-generation sequencing (NGS) techniques for variant detection has become
increasingly important in clinical research and in clinical practice in oncology. Many cancer …

Non-small cell lung cancer (NSCLC) encompasses distinct histopathological subtypes,
namely adenocarcinoma (AC) and squamous cell lung carcinoma (SCC), which require …

Due to predictions of increasing incidences and deaths from ovarian cancer, this neoplasm
is a challenge for modern health care. The advent of NGS technology has made it possible …

Over the past two decades, Next-Generation Sequencing (NGS) has revolutionized the
approach to cancer research. Applications of NGS include the identification of tumor specific …

Histopathology has historically been the critical technique for the diagnosis and treatment of
human disease. Today, genomics, transcriptomics, and proteomics from specific cells, rather …

Liquid biopsy-derived RNA sequencing (lbRNA-seq) exhibits significant promise for clinic-
oriented cancer diagnostics due to its non-invasiveness and ease of repeatability. Despite …

In biomedical research, validating a scientific discovery hinges on the reproducibility of its
experimental results. However, in genomics, the definition and implementation of …

Background The proto‐oncogene ROS1 encodes an intrinsic type I membrane protein of the
tyrosine kinase/insulin receptor family. ROS1 facilitates the progression of various …

Introduction Colorectal cancer (CRC) is one of the most prevalent and lethal cancers
worldwide. The treatment of metastatic colorectal cancer (mCRC) is difficult, and mCRC has …