Optical coherence tomography in coronary atherosclerosis assessment and intervention

M Araki, SJ Park, HL Dauerman, S Uemura… - Nature Reviews …, 2022 - nature.com
Since optical coherence tomography (OCT) was first performed in humans two decades ago,
this imaging modality has been widely adopted in research on coronary atherosclerosis and …

[HTML][HTML] Myocardial infarction with non-obstructive coronary artery disease: MI with non-obstructive coronary disease

B Lindahl, T Baron, M Albertucci, F Prati - EuroIntervention, 2021 - ncbi.nlm.nih.gov
As a result of the increased use of coronary angiography in acute myocardial infarction in
the last two decades, myocardial infarction with non-obstructive coronary arteries (MINOCA) …

Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II): a prospective natural history study

D Erlinge, A Maehara, O Ben-Yehuda, HE Bøtker… - The Lancet, 2021 - thelancet.com
Background Near-infrared spectroscopy (NIRS) and intravascular ultrasound are promising
imaging modalities to identify non-obstructive plaques likely to cause coronary-related …

Effect of alirocumab added to high-intensity statin therapy on coronary atherosclerosis in patients with acute myocardial infarction: the PACMAN-AMI randomized …

L Räber, Y Ueki, T Otsuka, S Losdat, JD Häner… - Jama, 2022 - jamanetwork.com
Importance Coronary plaques that are prone to rupture and cause adverse cardiac events
are characterized by large plaque burden, large lipid content, and thin fibrous caps. Statins …

Effect of evolocumab on coronary plaque phenotype and burden in statin-treated patients following myocardial infarction

SJ Nicholls, Y Kataoka, SE Nissen, F Prati… - Cardiovascular …, 2022 - jacc.org
Background The proprotein convertase subtilisin kexin type-9 inhibitor evolocumab
produced coronary atheroma regression in statin-treated patients. Objectives The purpose of …

Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT–FFR trial

E Kedhi, B Berta, T Roleder… - European heart …, 2021 - academic.oup.com
Aims The aim of this study was to understand the impact of optical coherence tomography
(OCT)-detected thin-cap fibroatheroma (TCFA) on clinical outcomes of diabetes mellitus …

Percutaneous coronary intervention for vulnerable coronary atherosclerotic plaque

GW Stone, A Maehara, ZA Ali, C Held… - Journal of the American …, 2020 - jacc.org
Background Acute coronary syndromes most commonly arise from thrombosis of lipid-rich
coronary atheromas that have large plaque burden despite angiographically appearing …

Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

P Gaba, BJ Gersh, J Muller, J Narula… - Nature Reviews …, 2023 - nature.com
Understanding the natural history of coronary artery atherosclerosis is necessary to
determine prognosis and prescribe effective therapies. Traditional management of coronary …

Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a …

SJ Park, JM Ahn, DY Kang, SC Yun, YK Ahn, WJ Kim… - The Lancet, 2024 - thelancet.com
Background Acute coronary syndrome and sudden cardiac death are often caused by
rupture and thrombosis of lipid-rich atherosclerotic coronary plaques (known as vulnerable …

[HTML][HTML] Intracoronary optical coherence tomography: state of the art and future directions: State of the art in OCT

Z Ali, KK Galougahi, GS Mintz, A Maehara… - …, 2021 - ncbi.nlm.nih.gov
Optical coherence tomography (OCT) has been increasingly utilised to guide percutaneous
coronary intervention (PCI). Despite the diagnostic utility of OCT, facilitated by its high …