Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions
N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …
from complex interplay between genetic and environmental factors. It is well-established that …
Extent of illicit drug use and dependence, and their contribution to the global burden of disease
L Degenhardt, W Hall - The Lancet, 2012 - thelancet.com
This paper summarises data for the prevalence, correlates, and probable adverse health
consequences of problem use of amphetamines, cannabis, cocaine, and opioids. We …
consequences of problem use of amphetamines, cannabis, cocaine, and opioids. We …
Psychosis as a transdiagnostic and extended phenotype in the general population
J Van Os, U Reininghaus - World Psychiatry, 2016 - Wiley Online Library
A large body of research indicates that weak expressions of positive psychotic symptoms
(“psychotic experiences”) can be measured in the general population, and likely represent …
(“psychotic experiences”) can be measured in the general population, and likely represent …
Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study
M Di Forti, A Marconi, E Carra, S Fraietta… - The Lancet …, 2015 - thelancet.com
Background The risk of individuals having adverse effects from drug use (eg, alcohol)
generally depends on the frequency of use and potency of the drug used. We aimed to …
generally depends on the frequency of use and potency of the drug used. We aimed to …
Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis
T Schoeler, A Monk, MB Sami, E Klamerus… - The Lancet …, 2016 - thelancet.com
Background Although the link between cannabis use and development of psychosis is well
established, less is known about the effect of continued versus discontinued cannabis use …
established, less is known about the effect of continued versus discontinued cannabis use …
The dopamine hypothesis of schizophrenia: version III—the final common pathway
OD Howes, S Kapur - Schizophrenia bulletin, 2009 - academic.oup.com
The dopamine hypothesis of schizophrenia has been one of the most enduring ideas in
psychiatry. Initially, the emphasis was on a role of hyperdopaminergia in the etiology of …
psychiatry. Initially, the emphasis was on a role of hyperdopaminergia in the etiology of …
Gone to pot–a review of the association between cannabis and psychosis
Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …
worldwide. Emerging evidence supports a number of associations between cannabis and …
A systematic review of the antipsychotic properties of cannabidiol in humans
TA Iseger, MG Bossong - Schizophrenia research, 2015 - Elsevier
Despite extensive study over the past decades, available treatments for schizophrenia are
only modestly effective and cause serious metabolic and neurological side effects …
only modestly effective and cause serious metabolic and neurological side effects …
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
THM Moore, S Zammit, A Lingford-Hughes… - The Lancet, 2007 - thelancet.com
Background Whether cannabis can cause psychotic or affective symptoms that persist
beyond transient intoxication is unclear. We systematically reviewed the evidence pertaining …
beyond transient intoxication is unclear. We systematically reviewed the evidence pertaining …
The neurodevelopmental hypothesis of schizophrenia, revisited
SH Fatemi, TD Folsom - Schizophrenia bulletin, 2009 - academic.oup.com
While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …
vast majority of evidence points to the neurodevelopmental model in which developmental …