Progress in definition, prevention and treatment of fungal infections in cystic fibrosis

C Schwarz, D Hartl, O Eickmeier, A Hector, C Benden… - Mycopathologia, 2018 - Springer
Cystic fibrosis (CF) is a chronic lethal multi-system condition; however, most of the morbidity
and mortality is dependent on the status of the respiratory system. Progressive respiratory …

The antiseptic Miramistin: a review of its comparative in vitro and clinical activity

A Osmanov, Z Farooq, MD Richardson… - FEMS microbiology …, 2020 - academic.oup.com
Miramistin is a topical antiseptic with broad antimicrobial action, including activity against
biofilms and a clinical profile showing good tolerability. Miramistin was developed within a …

Biofilm formation on titanium implants counteracted by grafting gallium and silver ions

A Cochis, B Azzimonti, C Della Valle… - … research Part A, 2015 - Wiley Online Library
Biofilm‐associated infections remain the leading cause of implant failure. Thanks to its
established biocompatibility and biomechanical properties, titanium has become one of the …

N-Chlorotaurine, a Promising Future Candidate for Topical Therapy of Fungal Infections

M Nagl, R Arnitz, M Lackner - Mycopathologia, 2018 - Springer
N-Chlorotaurine (NCT) is a mild long-lived oxidant that can be applied to sensitive body
regions as an endogenous antiseptic. Enhancement of its microbicidal activity in the …

Bactericidal and Fungicidal Activity of N-Chlorotaurine Is Enhanced in Cystic Fibrosis Sputum Medium

M Gruber, I Moser, M Nagl… - Antimicrobial Agents and …, 2017 - Am Soc Microbiol
Lung infections with multiresistant pathogens are a major problem among patients suffering
from cystic fibrosis (CF). N-Chlorotaurine (NCT), a microbicidal active chlorine compound …

[HTML][HTML] Activity of N-Chlorotaurine against Periodontal Pathogens

K Kowalczyk, DC Coraça-Huber… - International Journal of …, 2024 - mdpi.com
Dental plaque bacteria play an important role in the pathogenicity of periodontitis and peri-
implantitis. Therefore, antimicrobial agents are one means of treatment. N-chlorotaurine …

Successful treatment of a unique chronic multi-bacterial scalp infection with N-chlorotaurine, N-bromotaurine and bromamine T

AM Kyriakopoulos, M Nagl… - Access …, 2020 - microbiologyresearch.org
Microbial species can act in synergy to circumvent environmental stress conditions and
survive. In addition, biofilms are a serious public-health issue globally and constitute a …

Activity of N-Chlorotaurine against Long-Term Biofilms of Bacteria and Yeasts

V Grimus, DC Coraça-Huber, SJM Steixner, M Nagl - Antibiotics, 2021 - mdpi.com
Background: N-chlorotaurine (NCT), an antiseptic that originates from the human defense
system, has broad-spectrum microbicidal activity and is well tolerated by human tissue and …

[HTML][HTML] Long-Term Stability and Efficacy of NCT Solutions

GJ Staudinger, ZM Thomas, SE Hooper… - International Journal of …, 2024 - mdpi.com
To realize the potential for the use of N-chlorotaurine (NCT) in healthcare, a better
understanding of the long-term stability of the compound in water is needed. An array of …

Taurine Haloamines and Biofilm. Part I: Antimicrobial Activity of Taurine Bromamine and Chlorhexidine Against Biofilm Forming Pseudomonas aeruginosa

M Strus, M Walczewska, A Machul, D Mikołajczyk… - Taurine 9, 2015 - Springer
Formation of biofilm is observed in a majority of chronic bacterial skin infections such as non-
healing wounds. These infections are persistent as they show increased resistance to …