Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising in vitro model
system for studying neurodevelopment. However, current models remain limited in their …

Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …

Medulloblastoma is a highly malignant pediatric brain tumor characterized by its aggressive
nature and limited treatment options. Metabolic changes have recently emerged as key …

Neural stem cells (NSCs) persist in the adult mammalian brain and are able to give rise to
new neurons and glia throughout life. The largest stem cell niche in the adult mouse brain is …

Membrane lipids have been known to influence multiple signalling and cellular processes.
Dysregulation of lipids at the neuronal membrane is connected to a significant alteration of …

Bisphenol A (BPA) exposure is associated with a plethora of neurodevelopmental
abnormalities and brain disorders. Previous studies have demonstrated BPA-induced …

Progressive neuronal dysfunction and death are key features of neurodegenerative
diseases; therefore, promoting neurogenesis in neurodegenerative diseases is crucial. With …

The iPSC-derived 3D models are considered to be a connective link between 2D culture
and in vivo studies. However, the sensitivity of such 3D models is yet to be established. We …

Stem cells possess extraordinary capacities for self-renewal and differentiation, making
them highly valuable in regenerative medicine. Among these, neural stem cells (NSCs) play …

Oxygen is essential to fuel aerobic metabolism. Some species evolved mechanisms to
tolerate periods of severe hypoxia and even anoxia in their environment. Among them …