An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …

Highlights•Human coronaviruses use distinctand similar strategies to counteract innate
defenses.•Insights from SARS-CoV-2 will inspire research on endemic and epidemic …

Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of
deaths since its emergence in 2019. Innate immune antagonism by lethal CoVs such as …

Some respiratory viruses can cause a viral interference through the activation of the
interferon (IFN) pathway that reduces the replication of another virus. Epidemiological …

All respiratory viruses establish primary infections in the nasal epithelium, where efficient
innate immune induction may prevent dissemination to the lower airway and thus minimize …

Many COVID‐19 patients suffer from gastrointestinal symptoms and impaired intestinal
barrier function is thought to play a key role in Long COVID. Despite its importance, the …

SARS-CoV-2 exhibits a remarkable capability to subvert the host antiviral innate immune
system. This adeptness is orchestrated by viral proteins, which initially attempt to obstruct the …

All respiratory viruses establish primary infections in the nasal epithelium, where efficient
innate immune induction may prevent dissemination to the lower airway and thus minimize …

The worldwide spread of SARS-CoV-2 has led to a significant economic and social burden
on a global scale. Even though the pandemic has concluded, apprehension remains …

India saw a spike in COVID-19 cases in early 2023, and this wave of infection was attributed
to XBB sublineages of SARS-CoV-2 Omicron variant. The impact of XBB wave was …