Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …

Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

Brain-derived neurotrophic factor (BDNF) is widely accepted as being critical for neural and
synaptic plasticity throughout the nervous system. Recent work has shown that BDNF in the …

Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …

Rationale Exposure to social defeat (SD) induces a depressive phenotype, increased
ethanol seeking and consumption, accompanied by activation of the neuroinflammatory …

Drug addiction is a multifactorial disorder resulting from the complex interaction between
biological, environmental and drug-induced effects. Generally, stress is a well-known risk …

Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …

Fear extinction is impaired in some psychiatric disorders. Any treatment that facilitates the
extinction of fear is a way to advance the treatment of related psychiatric disorders. Recent …

Oxytocin (OXT) modulates social interactions, attenuates stressful responses and can
decrease drug-seeking and taking behaviors. In previous studies, we observed that social …

Social anxiety disorder (SAD) is a prevalent mental illness in both men and women, but
current treatment approaches with selective serotonin reuptake inhibitors (SSRI) have …