Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

Aim: We performed a systematic review and meta-analysis to investigate the efficacy and
safety of third-line (TLT) and salvage treatment (ST) in advanced or metastatic gastric …

Intratumoral heterogeneity (ITH) is a fundamental property of cancer; however, the origins of
ITH remain poorly understood. We performed single-cell transcriptome profiling of peritoneal …

Background The monoclonal antibody zolbetuximab (formerly IMAB362), which is being
developed as a potential treatment for gastric cancer (GC), targets Claudin 18.2 (CLDN18 …

Abstract Background and Aim Metabolic reprogramming is characterized by dysregulated
levels of metabolites and metabolic enzymes. Integrated metabolomic and transcriptomic …

URI, a prefoldin family member, has been implicated roles in cancer development. We have
previously shown that URI can attenuate DNA damage in gastric cancer cells treated with …

Osthole is an active compound isolated from Chinese herb Cnidium monnieri (L.) Cusson,
and had been reported to possess antitumor effect. However, the effect of osthole on the …

Purpose The purpose of this study was to investigate the relationship between microRNA-
29b-3p (miR-29b-3p) and myc-associated zinc finger protein (MAZ) expression and the …

Introduction: Tumor tissue sample is currently the gold standard for diagnosing
gastrointestinal cancers, but also for genomic/immune component analyses that can help in …

Gastric cancer (GC) is the second leading cause of cancer mortality and the fourth most
commonly diagnosed malignant diseases. While continued efforts have been focused on …